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Before you get a good answer, sometimes you need to ask the right question. The Priority Setting Partnership (PSP) for Hip and Knee Replacement for Osteoarthritis (OA) reached the end of its process in March this year, producing a list of ten priority areas for further research funding. These are questions that the combined group of healthcare professionals and patients / carers have concluded need addressing first to help continued progress in treating this area of patient health.
Nirmatrelvir-ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022-23: virological and immunological results of an open-label randomised trial (PANORAMIC).
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Lowe DM. et al, (2027), Lancet Microbe
Multi-objective optimisation of 3D-printed multilayer TPMS osteochondral scaffolds for enhanced mechanical and biological performance
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Xu Y. et al, (2026), Virtual and Physical Prototyping, 21
Subharmonics are not an infallible safety metric for cavitation dynamics.
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Wu Q. et al, (2026), Int J Hyperthermia, 43
Assessing the Importance of Variation in Diagnostic Coding Among the Three Countries in the UK Biobank
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Clifton L. et al, (2026), Learning Health Systems, 10
Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL
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Coates LC. et al, (2026), RMD Open, 20, e043855 - e043855
Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature.
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Scherlinger M. et al, (2026), J Transl Autoimmun, 12
Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023).
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Perletta V. et al, (2026), ESMO Real World Data Digit Oncol, 12
Recent advances in biomaterials and structural design of 3D printed multiphasic scaffolds for osteochondral regeneration
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Xu Y. et al, (2026), Materials Science and Engineering: R: Reports, 170, 101210 - 101210
Volumetric Additive Manufacturing of Embedded Channels for Studying Flow and Permeation in Hydrogel Systems
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Stride E., (2026), Advanced Materials Technologies
Hedgehog Inhibitor and Paclitaxel: A Phase I Trial of the Oral Hedgehog inhibitor Taladegib in Combination with Weekly Paclitaxel in Patients with Advanced Solid Tumours.
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Glasspool R. et al, (2026), Invest New Drugs
Age and symptom severity as predictors of outcomes following shockwave therapy in Achilles tendinopathy : a single-centre observational study.
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Hutchison A-M. et al, (2026), Bone Joint J, 108-B, 650 - 656
Reoperation in the year following a hip fracture : a nationwide cohort study in England.
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Patel R. et al, (2026), Bone Joint J, 108-B, 698 - 706
Deformation-Recovery diffusion model (DRDM): Instance deformation for image manipulation and synthesis.
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Zheng J-Q. et al, (2026), Med Image Anal, 110
The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care.
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Sharma A. et al, (2026), BJU Int, 137, 849 - 857
Medium-term recovery of patients with complex lower limb fractures : follow-up study of fracture types in the Wound Healing in Surgery for Trauma (WHIST) trial.
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Goh EL. et al, (2026), Bone Joint J, 108-B, 681 - 687
Identifying the Initiation of a New Line of Therapy for Metastatic Lung, Breast, and Colorectal Cancer in Real-World Data: A Scoping Review.
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Onasanya O. et al, (2026), Pharmacoepidemiol Drug Saf, 35
Identification of genetic risk loci associated with aquaporin 4-positive neuromyelitis optica spectrum disorder: a genome-wide association study.
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Attfield KE. et al, (2026), Lancet Neurol, 25, 482 - 491
Microbubbles manufactured using a tissue homogeniser: DoE-guided optimisation for a narrower size distribution and higher yield.
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O'Reilly CS. et al, (2026), Int J Pharm
Comparison of ultrasound contrast agent production by sonication and mechanical agitation
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Stride E., (2026), Ultrasonics Sonochemistry
Resolving the mechanical paradox of myelination.
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Fritzsche M., (2026), Commun Biol, 9