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A new study of open leg fractures suggests there is no difference to patient recovery whether high-tech negative pressure wound therapy devices are used, compared to standard dressings.
Methods for the development and validation of computable phenotypes based on biobanks and linked real world data
Deadline - Friday 15 May 2026
Meet the team
-
Matthew Costa
Professor of Orthopaedic Trauma Surgery
Read the paper
In The Journal of the American Medical Association (JAMA)
Professor Matt Costa talks about the study
More information
- Conducted by Warwick Clinical Trials Unit, the University of Warwick, University Hospitals Coventry and Warwickshire NHS Trust, and NDORMS
- Results have implications for patients' recovery and healthcare costs
- This project was funded by the UK NIHR HTA Programme (project No. 10/57/20) and was supported by the NIHR Oxford Biomedical Research Centre and the NIHR Collaboration for Leadership in Applied Health Research and Care in Oxford. The 2 main commercial entities (Smith & Nephew and KCI Medical) in this sector funded the excess treatment costs of the negative pressure wound therapy dressings but had no part in the design, conduct, or reporting of the trial.