New therapeutic target identified in spondyloarthritis

Nirmatrelvir-ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022-23: virological and immunological results of an open-label randomised trial (PANORAMIC).

Lowe DM. et al, (2027), Lancet Microbe

Multi-objective optimisation of 3D-printed multilayer TPMS osteochondral scaffolds for enhanced mechanical and biological performance

Xu Y. et al, (2026), Virtual and Physical Prototyping, 21

Subharmonics are not an infallible safety metric for cavitation dynamics.

Wu Q. et al, (2026), Int J Hyperthermia, 43

Assessing the Importance of Variation in Diagnostic Coding Among the Three Countries in the UK Biobank.

Clifton L. et al, (2026), Learn Health Syst, 10

Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL

Coates LC. et al, (2026), RMD Open, 20, e043855 - e043855

Assessing interannual variation in leaf chlorophyll dynamics using optical and destructive methods with mixed-effects and additive modelling

Khan R., (2026), Journal of Plant Research

Atlas of human gut-associated lymphoid tissue reveals immunomodulatory interactions of B cells.

Pitcher MJ. et al, (2026), Sci Immunol, 11

Certolizumab Inhibits Radiographic Progression in Patients with Early Rheumatoid Arthritis and High Rheumatoid Factor Levels: A Pooled, Post‑Hoc Analysis of the Phase 3 C‑EARLY and C‑OPERA Trials

Smolen JS. et al, (2026), Joint Bone Spine

Optimal blood pressure target in patients with uncomplicated hypertension: a target trial emulation study

Zhang R. et al, (2026), Nature Communications

Step count recovery patterns in the first six weeks after knee replacement in individuals with knee osteoarthritis: a secondary analysis of a prospective observational cohort study using wrist-worn accelerometry.

Olanrewaju AE. et al, (2026), Rheumatol Int, 46

Association between surgeon experience, level of supervision, and outcomes after hip fracture.

Goh EL. et al, (2026), Bone Jt Open, 7, 744 - 752

A qualitative exploration of the barriers and facilitators for engagement with a self-led biopsychosocial support tool, Pain Rehabilitation to Optimize Major Orthopaedic Trauma REcovery (PROMOTE), for patients with complex lower-limb orthopaedic trauma.

Fordham B. et al, (2026), Bone Jt Open, 7, 724 - 732

Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum.

Perry TA. et al, (2026), Nat Commun, 17

District-level healthcare accessibility under flood-conditioned road network disruption in Pakistan

Khan R. et al, (2026), Spatial Information Research

National patient-reported outcome measures data and the National Joint Registry : a report on the data completeness and quality.

Singh Benning M. et al, (2026), Bone Joint J, 108-B, 773 - 780

Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023).

Perletta V. et al, (2026), ESMO Real World Data Digit Oncol, 12

Pain Rehabilitation to Optimize Major Orthopaedic Trauma REcovery (PROMOTE) compared with routine care : a multicentre, parallel-group, randomized feasibility trial with an embedded qualitative study.

Fordham B. et al, (2026), Bone Joint J, 108-B, 818 - 826

Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults-A Pilot Study.

Alsaleh G. et al, (2026), Aging Cell, 25

Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature.

Scherlinger M. et al, (2026), J Transl Autoimmun, 12

Prescription cascades associated with acetylcholinesterase inhibitors use: a high-throughput sequence symmetry analysis

Newby D. et al, (2026), Age and Ageing

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Nirmatrelvir-ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022-23: virological and immunological results of an open-label randomised trial (PANORAMIC).

Multi-objective optimisation of 3D-printed multilayer TPMS osteochondral scaffolds for enhanced mechanical and biological performance

Subharmonics are not an infallible safety metric for cavitation dynamics.

Assessing the Importance of Variation in Diagnostic Coding Among the Three Countries in the UK Biobank.

Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL

Assessing interannual variation in leaf chlorophyll dynamics using optical and destructive methods with mixed-effects and additive modelling

Atlas of human gut-associated lymphoid tissue reveals immunomodulatory interactions of B cells.

Certolizumab Inhibits Radiographic Progression in Patients with Early Rheumatoid Arthritis and High Rheumatoid Factor Levels: A Pooled, Post‑Hoc Analysis of the Phase 3 C‑EARLY and C‑OPERA Trials

Optimal blood pressure target in patients with uncomplicated hypertension: a target trial emulation study

Step count recovery patterns in the first six weeks after knee replacement in individuals with knee osteoarthritis: a secondary analysis of a prospective observational cohort study using wrist-worn accelerometry.

Association between surgeon experience, level of supervision, and outcomes after hip fracture.

A qualitative exploration of the barriers and facilitators for engagement with a self-led biopsychosocial support tool, Pain Rehabilitation to Optimize Major Orthopaedic Trauma REcovery (PROMOTE), for patients with complex lower-limb orthopaedic trauma.

Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum.

District-level healthcare accessibility under flood-conditioned road network disruption in Pakistan

National patient-reported outcome measures data and the National Joint Registry : a report on the data completeness and quality.

Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023).

Pain Rehabilitation to Optimize Major Orthopaedic Trauma REcovery (PROMOTE) compared with routine care : a multicentre, parallel-group, randomized feasibility trial with an embedded qualitative study.

Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults-A Pilot Study.

Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature.

Prescription cascades associated with acetylcholinesterase inhibitors use: a high-throughput sequence symmetry analysis

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