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Study reveals the three most important aspects of care for hip fractures
5 May 2021
Older patients with hip fractures recover better if they receive treatment under the supervision of both a surgeon and a specialist in elderly care; are checked to avoid future falls; and are assessed for memory problems.
The role of mAbs (neutralising monoclonal antibodies) in the fight against COVID-19
30 April 2021
Neutralising mAbs, a form of anti-viral medicine, are being explored as an attractive option to treat symptoms of COVID-19 and in some cases prevent infection. But what are the pros and cons of this type of treatment and what should regulators consider before granting approval?
Small mechanical forces in immune cells measured at unprecedented sensitivity
16 April 2021
Oxford researchers have used advanced microscopy techniques to measure previously unseen forces generated by cells during an immune response; a breakthrough for mechanobiology and future advances in health and disease.
Cognitive–behavioural therapy consistently improves quality of life
26 February 2021
Main Rehabilitation and self-management Research
A meta-review of the available research into cognitive behavioural therapy reveals it consistently improves health-related quality of life across different medical conditions and demographic populations.
Oxford to collaborate with Janssen to map the cellular landscape of immune mediated disorders
19 February 2021
The University of Oxford has entered into a strategic collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.
WHiTE Four trial results published
9 February 2021
Hip Main Orthopaedics and trauma Research Trauma
The results of the WHiTE Four clinical trial for the treatment of fragility hip fractures have been published in The Bone and Joint Journal.
Understanding the first wave of COVID-19 and implications for tackling the ongoing pandemic: evidence from 5.5 million people from Catalonia, Spain
3 February 2021
Botnar Main Research Statistics and epidemiology
Health outcomes during the first wave of COVID-19 in Catalonia, Spain, have been described in detail in a study published by Nature Communications.
Immunology preprint reviews launched in Nature Reviews Immunology
15 January 2021
The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.
Living reviews launched by Oxford and Cardiff in the wake of COVID-19 research
18 December 2020
In a combined effort to help COVID-19 researchers the University of Oxford and Cardiff University have launched a series of “living reviews” in Oxford University Press’s new open access journal “Oxford Open Immunology”.
3D imaging reveals the role of blood vessels in hormone production
11 December 2020
New research from the Kusumbe Group at the Kennedy Institute has shown a direct correlation between age-related decline in capillary and artery numbers and hormone production in the endocrine system.
Could do better: clinical trial reporting fails to live up to the mark
8 June 2020
The statistical analysis and reporting of treatment effects in reports of randomised trials with a binary primary endpoint requires substantial improvement, suggests NDORMS research published in BMC Medicine.
Study reveals how cancer cells use bone marrow fat for growth and survival
17 January 2020
As society battles with an obesity epidemic, new research from the Edwards group shows how increased body fat contributes to cancer establishment and progression.
Cancer progression may be controlled by targeting tumor-specific extracellular matrix
15 January 2020
Kennedy Main Oncology Research
Researchers have uncovered how tumors exploit tenascin-C to deflect the body’s natural defence against them.
New collaboration aims to shape future drug development
18 December 2019
The EU-PEARL project will take a systematic approach that enables patient-focused, cross company collaborative platform trials.
Researchers identify link in the treatment of inflammatory bowel disease (IBD)
6 December 2019
A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance
Study reveals ‘postcode lottery’ for hip and knee replacement physiotherapy
5 December 2019
Post-operation physiotherapy following hip and knee replacement varies significantly across the UK according to new research by Dr Toby Smith, leading to a ‘postcode lottery’ for patients.
Cancer Research UK Senior Fellowship awarded to John Christianson
2 December 2019
John Christianson, Associate Professor at NDORMS, has been awarded a £2 million Cancer Research UK Senior Cancer Research Fellowship to explore new treatments for patients with multiple myeloma.
Platelet rich plasma found to be of no benefit in treating torn Achilles tendon
20 November 2019
New research from the University of Oxford has shown that platelet rich plasma (PRP) is not effective in treating acute Achilles tendon ruptures.
Dissecting TNF signalling in inflammatory disease
28 October 2019
Inflammation biology Kennedy Main Research
New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.
Protective mediators can help heal injured tendon cells by attacking inflammation
11 October 2019
Inflammation biology Main Research
Findings reported in The American Journal of Pathology suggest specialized proresolving mediators may become therapeutics that alleviate chronic tendon inflammation