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New Research from the Kusumbe group at the Kennedy Institute of Rheumatology identifies vascular attrition, marked by pericyte to fibroblast differentiation, as a primary hallmark of aging and highlights organ-specific vascular changes with age.

A montage of images showing 3D scans of mouse spleens and kidneys
From left to right 1 - Tile scan 3D confocal image showing a mouse spleen with multicolour immunolabeling for endothelial cell and pericyte markers. Blue shows cell nuclei stained with TO-PRO-3. 2 - Tile scan 3D confocal image showing a mouse spleen with multicolour immunolabeling for endothelial cell and pericyte markers. 3 - Tile scan 3D confocal image showing a mouse kidney with multicolour immunolabeling for endothelial cell and pericyte markers. Blue shows cell nuclei stained with TO-PRO-3. 4 - Tile scan 3D confocal image showing a mouse kidney with multicolour immunolabeling for endothelial cell and pericyte markers.

Research Assistant in Immunology and Inflammation (185107)

With several clinical studies currently active in the lab you will be part of the team investigating the cellular and molecular response of patients to standard of care treatments and biologics for diseases including Rheumatoid Arthritis and Inflammatory Bowel Disease.

Senior Postdoctoral Research Assistant in Immunology (184983)

We're looking for an experienced postdoctoral researcher to join the Experimental Medicine Collaboration (EMC) for drug discovery, target validation and clinical development of new drug therapies.

Postdoctoral Research Assistant in Spatial Biology & Bioinformatics (185130)

Do you have a background in bioinformatics and spatial genomics? Join the Kennedy Institute as our new Postdoctoral Research Assistant.

Find out more about the Kusumbe Group

Specialized blood vessels (green/yellow) form nurturing niches for osteoprogenitor cells (white) in bone 

    Kusumbe Group

 

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