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A case of Erdheim-Chester disease which affected the epiphysis and showed evidence of systemic disease is presented. Clinical and histopathological similarities with other forms of disseminated Langerhans' cell histiocytosis are noted, particularly reaction of infiltrating histiocytes for S100 and HLA-DR.

Original publication

DOI

10.1136/jcp.46.5.481

Type

Journal article

Journal

Journal of clinical pathology

Publication Date

05/1993

Volume

46

Pages

481 - 482

Addresses

Department of Pathology, Nuffield Orthopaedic Centre, Oxford.

Keywords

Epiphyses, Tibia, Foam Cells, Histiocytes, Humans, Osteosclerosis, Histiocytosis, Langerhans-Cell, Aged, Male