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OBJECTIVES: To develop European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis. METHODS: An expert group (10 rheumatologists, 3 nephrologists, 2 immunolgists, 2 internists representing 8 European countries and the USA, a clinical epidemiologist and a representative from a drug regulatory agency) identified 10 topics for a systematic literature search through a modified Delphi technique. In accordance with standardised EULAR operating procedures, recommendations were derived for the management of large vessel vasculitis. In the absence of evidence, recommendations were formulated on the basis of a consensus opinion. RESULTS: Seven recommendations were made relating to the assessment, investigation and treatment of patients with large vessel vasculitis. The strength of recommendations was restricted by the low level of evidence and EULAR standardised operating procedures. CONCLUSIONS: On the basis of evidence and expert consensus, management recommendations for large vessel vasculitis have been formulated and are commended for use in everyday clinical practice.

Original publication

DOI

10.1136/ard.2008.088351

Type

Journal article

Journal

Annals of the rheumatic diseases

Publication Date

03/2009

Volume

68

Pages

318 - 323

Addresses

University of Oxford, Oxford, UK.

Keywords

European Vasculitis Study Group, Humans, Vasculitis, Aspirin, Inflammation Mediators, Immunosuppressive Agents, Glucocorticoids, Drug Monitoring, Drug Therapy, Combination, Evidence-Based Medicine, Takayasu Arteritis, Giant Cell Arteritis