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In a group of eighty-three patients with untreated Paget's disease of bone, plasma alkaline phosphatase activity (AP), plasma non-protein-bound hydroxyproline concentration (PHP) and urinary excretion rate of total hydroxyproline (THP) were closely correlated with each other but not with fasting plasma concentrations of calcium or inorganic phosphate. Probit plots of AP and THP showed log-normal distributions overlapping the normal ranges.

Original publication

DOI

10.1111/j.1365-2362.1977.tb01567.x

Type

Journal article

Journal

European journal of clinical investigation

Publication Date

02/1977

Volume

7

Pages

37 - 39

Keywords

Humans, Osteitis Deformans, Phosphates, Calcium, Alkaline Phosphatase, Hydroxyproline, Adult, Aged, Middle Aged, Female, Male