NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release.

Bezbradica JS., Joyce S.

The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to instruct inflammasome-independent IL-1β release.

DOI

10.1016/j.celrep.2020.03.045

Type

Journal article

Journal

Cell rep

Publication Date

07/04/2020

Volume

31

Keywords

Cytokines, Inflammasomes, Interleukin-1beta, Natural Killer T-Cells

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