Prophylactic uses of fully reduced forms of hmgb1 prior to injury
NANCHAHAL J., Espirito Santo A., Lee G., Feldmann M., HORWOOD N.
The subject invention provides a method of preventing a consequence of an anticipated injury in a subject which comprises administering to the subject a therapeutically effective amount of the fully reduced (all thiol) form of HMGB1 or a biologically active truncated form of HMGB1, so as to prevent the consequence of the anticipated injury.