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A term infant with congenital varicella syndrome (CVS) is reported. Monoplegia of the left arm and paraplegia were present with no evidence of dermatomal skin scarring. Following death at 12 days of age, autopsy documented severe atrophy and gliosis of the spinal cord. Testing for varicella-zoster virus by the polymerase chain reaction method on brain tissue was positive. This case extends the current understanding of the clinical and pathological features of CVS.

Original publication

DOI

10.1046/j.1440-1754.2000.00479.x

Type

Journal article

Journal

Journal of paediatrics and child health

Publication Date

04/2000

Volume

36

Pages

186 - 188

Addresses

Departments of Neonatology and Pathology, Royal Alexandra Hospital for Children and Virology Unit ICPMR, Westmead Hospital, Westmead, New South Wales, Australia.

Keywords

Toes, Spinal Cord, Cicatrix, Skin, Humans, Chickenpox, Hand Deformities, Congenital, Syndrome, Polymerase Chain Reaction, Infant, Newborn, Female