Inflammatory insults affect platelet production, but it is yet unknown what mechanisms can drive rapid adaptations in thrombopoiesis. In this issue of Immunity, Petzold et al. (2022) propose that neutrophils "pluck" on megakaryocytes in the bone marrow to tune platelet release.
Journal article
Immunity
13/12/2022
55
2217 - 2219
Blood Platelets, Neutrophils, Thrombopoiesis, Megakaryocytes, Bone Marrow