A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding

Wang C., Philpott M., O'Brien D., Ndungu K., Malzahn J., Maritati M., Mehta N., Gamble V., Martinez-Burgo B., Bonham S., Fischer R., Garbutt K., Becker C., Manek S., Harris A., Sacher F., Obendorf M., Schmidt N., Mueller J., Zollner T., Zondervan K., Kessler B., Oppermann U., Cribbs A.

DOI

10.1101/2024.02.06.578872

Type

Preprint

Publication Date

08/02/2024

Keywords

splicing, multi-omic integrative analysis, heavy menstrual bleeding, long-read sequencing, uterine fibroids, MED12, single cell analysis, differential transcript usage

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