Figure 3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA., Liu X., Littlejohns TJ., Cuzick J., Clifton L., Hunter DJ.
<p>Decision curve analysis for Tyrer–Cuzick and Gail 10-year risk scores with and without PRS<sub>BC</sub> in test data (<i>N</i> = 25,359). Plots show net benefit calculated in full available follow-up time. The gray line indicates net benefit if all women were screened, and the black line indicates net benefit if no women were screened.</p>