Figure 3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA., Liu X., Littlejohns TJ., Cuzick J., Clifton L., Hunter DJ.
Decision curve analysis for Tyrer–Cuzick and Gail 10-year risk scores with and without PRSBC in test data (N = 25,359). Plots show net benefit calculated in full available follow-up time. The gray line indicates net benefit if all women were screened, and the black line indicates net benefit if no women were screened.