Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

Original publication

DOI

10.1084/jem.20100780

Type

Journal article

Journal

J Exp Med

Publication Date

10/05/2010

Volume

207

Pages

907 - 909

Keywords

Actins, Animals, B-Lymphocytes, Cytoskeletal Proteins, Genetic Engineering, Immunological Synapses, Lymphocyte Activation, Mice, Models, Immunological, Receptors, Antigen, B-Cell, Signal Transduction, T-Lymphocytes