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Osteoarthritis (OA) has been shown to be associated with decreased physical function, which may impact upon a person's self-rated health (SRH). Only a few studies have examined the association between OA and SRH in the general population, but to date none have used a clinical definition of OA. The objectives are: (1) To examine the cross-sectional association between clinical OA and fair-to-poor SRH in the general population; (2) To examine whether this association differs between countries; (3) To examine whether physical function is a mediator in the association between clinical OA and SRH.Baseline data of the European Project on OSteoArthritis (EPOSA) were used, which includes pre-harmonized data from six European cohort studies (n = 2709). Clinical OA was defined according to the American College of Rheumatology criteria. SRH was assessed using one question: How is your health in general? Physical function was assessed using the Western Ontario and McMaster Universities OA Index and Australian/Canadian OA Hand Index.The prevalence of fair-to-poor SRH ranged from 19.8 % in the United Kingdom to 63.5 % in Italy. Although country differences in the strength of the associations were observed, clinical OA of the hip, knee and hand were significantly associated with fair-to-poor SRH in five out of six European countries. In most countries and at most sites, the association between clinical OA and fair-to-poor SRH was partly or fully mediated by physical function.Clinical OA at different sites was related to fair-to-poor SRH in the general population. Most associations were (partly) mediated by physical functioning, indicating that deteriorating physical function in patients with OA should be a point of attention in patient care.

Original publication

DOI

10.1007/s11136-015-1171-8

Type

Journal article

Journal

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Publication Date

06/2016

Volume

25

Pages

1423 - 1432

Addresses

Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center Research, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands. nm.vanschoor@vumc.nl.

Keywords

Hand, Humans, Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Sickness Impact Profile, Prevalence, Cohort Studies, Cross-Sectional Studies, Health Status, Quality of Life, Aged, Aged, 80 and over, Europe, Germany, Italy, Netherlands, Sweden, Spain, Female, Male, Self Report, United Kingdom