Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The PROximal Fracture of the Humerus Evaluation by Randomisation (PROFHER) randomised clinical trial compared the operative and non-operative treatment of adults with a displaced fracture of the proximal humerus involving the surgical neck. The aim of this study was to determine the long-term treatment effects beyond the two-year follow-up.Of the original 250 trial participants, 176 consented to extended follow-up and were sent postal questionnaires at three, four and five years after recruitment to the trial. The Oxford Shoulder Score (OSS; the primary outcome), EuroQol 5D-3L (EQ-5D-3L), and any recent shoulder operations and fracture data were collected. Statistical and economic analyses, consistent with those of the main trial were applied.OSS data were available for 164, 155 and 149 participants at three, four and five years, respectively. There were no statistically or clinically significant differences between operative and non-operative treatment at each follow-up point. No participant had secondary shoulder surgery for a new complication. Analyses of EQ-5D-3L data showed no significant between-group differences in quality of life over time.These results confirm that the main findings of the PROFHER trial over two years are unchanged at five years. Cite this article: Bone Joint J 2017;99-B:383-92.

Original publication

DOI

10.1302/0301-620x.99b3.bjj-2016-1028

Type

Journal article

Journal

The bone & joint journal

Publication Date

03/2017

Volume

99-B

Pages

383 - 392

Addresses

Teesside University, Middlesbrough, Tees Valley TS1 3BA, UK.

Keywords

Shoulder Joint, Humans, Shoulder Fractures, Treatment Outcome, Fracture Fixation, Follow-Up Studies, Recovery of Function, Quality of Life, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Young Adult