Comparing different ways of calculating sample size for a randomised controlled trial using baseline and post-intervention measurements
Clifton L., Birks J., Clifton D.
In this paper, we compare different methods of calculating sample sizes for comparing two independent means of a continuous outcome with baseline and post-intervention measurements of a randomised controlled trial (RCT). Sample size calculations typically use published results from similar trials, and we illustrate the different methods using published results from the MOSAIC trial.