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Guidance is provided in a European setting on the assessment and treatment of postmenopausal women at risk from fractures due to osteoporosis. INTRODUCTION: The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2013. This manuscript updates these in a European setting. METHODS: Systematic reviews were updated. RESULTS: The following areas are reviewed: the role of bone mineral density measurement for the diagnosis of osteoporosis and assessment of fracture risk; general and pharmacological management of osteoporosis; monitoring of treatment; assessment of fracture risk; case-finding strategies; investigation of patients; health economics of treatment. The update includes new information on the evaluation of bone microstructure evaluation in facture risk assessment, the role of FRAX® and Fracture Liaison Services in secondary fracture prevention, long-term effects on fracture risk of dietary intakes, and increased fracture risk on stopping drug treatment. CONCLUSIONS: A platform is provided on which specific guidelines can be developed for national use.

Original publication

DOI

10.1007/s00198-018-4704-5

Type

Journal article

Journal

Osteoporos int

Publication Date

01/2019

Volume

30

Pages

3 - 44

Keywords

Bone mineral density, Diagnosis of osteoporosis, FRAX, Fracture risk assessment, Health economics, Treatment of osteoporosis, Absorptiometry, Photon, Bone Density, Bone Density Conservation Agents, Europe, Female, Humans, Life Style, Osteoporosis, Postmenopausal, Osteoporotic Fractures, Risk Assessment, Risk Factors