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The Oxford EMCRF launches new bone marrow biopsy capability to expand research support
4 November 2024
The NIHR Oxford Clinical Research Facility (EMCRF) has expanded its support of medical research trials by offering bone marrow biopsies for the first time.
HIPCARE trial launches in the Philippines
22 April 2024
Prof Matt Costa has just returned from the Philippines, where he launched the new HIPCARE trial with co-lead investigator Prof Irewin Tabu. The first of five Low- and Middle-Income Countries (LMIC) in Asia to take part, eight hospitals in the Philippines will start recruiting patients with fragility fractures of the hip to the study within weeks.
New bronchoscopy capability expands capacity for respiratory and vaccine trials
14 March 2024
The NIHR Oxford Clinical Research Facility (EMCRF) hosted by NDORMS has expanded its capability to undertake research bronchoscopies. The facility welcomed its first volunteers as part of the Oxford Airways Study to help understand the causes of asthma.
Lymph node research pioneers' new approach to vaccine design for the most vulnerable
17 January 2024
The Oxford Experimental Medicine Clinical Research Facility (EMCRF) at NDORMS has received its first volunteers as part of the LEGACY03 trial to improve vaccine design for different age groups.
New research endoscopy service launches today
2 October 2023
The launch of a new endoscopy service at the Oxford Experimental Medicine Clinical Research Facility (EMCRF) will enhance the collection of data for research projects at NDORMS and across the University of Oxford.
Psoriatic arthritis awareness day - a patients story
28 September 2023
The early warning signs of psoriatic arthritis (PsA) can be hard to spot. Any delay in diagnosis of PsA can leave patients uncomfortable and in pain. But slow diagnosis is all too common, according to Professor Laura Coates. She is leading a new study called HPOS, that is looking for 2000 UK volunteers to chart their psoriasis symptoms, and which may help to explain why one third of psoriasis patients to go on to develop arthritis.
Going straight to surgery found to be better than undergoing rehabilitation first for longstanding anterior cruciate ligament injury
23 August 2022
New research, funded by the National Institute for Health and Care Research (NIHR), shows initial surgery to be more successful and cost effective than undergoing treatment with rehabilitation first to treat longstanding anterior cruciate ligament injury.
Emergency departments to use the FORCE pathway for wrist fractures in children
6 July 2022
New research from the University of Oxford has shown that doctors can simplify treatment for the most common fracture in children, reducing NHS costs.
Taking a break from immune-suppressing medicines doubles the antibody response to COVID-19 booster vaccination
29 June 2022
The Oxford Clinical Trials Research Unit (OCTRU) at NDORMS played a key role in the VROOM study which found that pausing immune-suppressing medicines such as methotrexate can increase the response to COVID-19 booster jabs.
Celebrating Clinical Trials Day at NDORMS
20 May 2022
To mark Clinical Trials Day we take a look at some of the recent developments at NDORMS and celebrate the teams that make this important area of our research programme possible.
Cemented hip replacement improves quality of life for patients over 60
10 February 2022
The White 5 trial compared implants fixed with bone cement against uncemented implants for hip fractures treated with hemiarthroplasty.
New centre aims to help companies conduct more efficient trials
26 February 2021
A new clinical therapeutics centre has been set up by the University of Oxford to help life sciences companies identify interventions that have the greatest potential to deliver patient benefit, and so bring down the cost of early phase clinical trials.
Oxford researchers start new trial on the use of anti-TNF to treat Covid-19 in care homes
30 September 2020
Researchers at the University of Oxford are starting a new study to explore the effectiveness of the anti-tumour necrosis factor (anti-TNF) drug adalimumab as a treatment for patients with COVID-19 in the community, especially care homes. The AVID-CC trial, which will be conducted by Oxford Clinical Trials Research Unit (OCTRU), will enrol up to 750 patients from community care settings throughout the UK.
Oxford leads part of major COVID-19 drugs trial
10 June 2020
NDORMS Professor Duncan Richards and Dr Matt Rowland (Nuffield Department of Clinical Neurosciences) are leading the Oxford arm of a new UK trial to investigate whether administering the anti-inflammatory drug infliximab to patients with COVID-19 can prevent progression to respiratory failure or death.
Managing clinical trials during the pandemic
4 May 2020
Duncan Richards, Climax Professor of Clinical Therapeutics and Director of the Oxford Clinical Trials Research Unit (OCTRU) is interviewed about clinical trials and the challenges of running them in a pandemic.
Professor Dan Perry Highly Commended in the VC PER Awards
28 August 2019
Professor Daniel Perry was recently Highly Commended in the Vice Chancellors Public Engagement with Research Awards for his work involving parents and children in the research process.
Increased use of partial knee replacement could save the NHS £30 million per year
17 July 2019
New research from a randomised clinical trial published today in The Lancet and funded by the National Institute for Health Research (NIHR) shows that partial knee replacements (PKR) are as good as total knee replacements (TKR), whilst being more cost effective.
Pills as good as injections to treat bone and joint infections, paper finds
8 February 2019
Pills are just as effective as intravenous (IV) injections in tackling bone infections, a study led by Oxford-based researchers has found.