Search results

MErCuRIC-1

This is a multi-centre European Phase 1 study of MEK1/2 inhibitor PD-0325901 with c-MET inhibitor PF-02341066 in KRASMT and KRASWT (with aberrant c-MET) Colorectal Cancer Patients.

UK-TAVI

The UK TAVI trial is a multi-centre randomised controlled trial to assess the clinical effectiveness and cost-utility of TAVI, compared with conventional surgical aortic valve replacement, in patients with severe symptomatic aortic stenosis, who are at intermediate or high operative risk.

RAMPP

This is a multi-centre randomised study investigating ambulatory chest catheter drainage devices in the treament of primary pneumothorax.

POISE

Clinical effectiveness of symptomatic therapy compared to standard step up care for the treatment of low impact psoriatic oligoarthritis: a 2 arm parallel group feasibility study

BIOYARN

A feasibility and efficacy trial evaluating a suturing augmentation device for rotator cuff repairs

HAND OA

More information coming soon

MACRO

This NIHR Programme aims to provide high quality evidence to establish best practice for the management of this common sinus disease. The large multi-disciplinary MACRO research team have come together to tackle the disease from many different aspects – across primary and secondary care, and from a clinical, economic and patient perspective.

PARCS

More information coming soon.

PURAK

This is an international study investigating wearable devices for distal arm functionality rehabilitation

STARR2

Delivering personalised care in the management of exacerbations of chronic obstructive pulmonary disease: A multi-centre randomised clinical trial.

SPECTRUM

More information coming soon

NINJA

The NINJA study is a pilot study which will assess whether a study that looks at whether nail plates should be discarded or replaced after nail bed injury in children is feasible in the NHS.

CEeDD

CEeDD: A phase I / II study to investigate the safety and feasibility of CavitationEnhanced Drug Delivery to solid tumours by co‐administration of sonosensitive particles and application of extracorporeal ultrasound

ANVIL

Anti-neutrophil cytoplasm antibody associated vasculitis treated with Interleukin-2 (ANVIL) therapy: proof of concept study.

PROMOTE IR800 IAB2M (Stage 2)

This is a single-centre study in those with high-risk prostate cancer.

OCTO-ART

This is a single centre observational study to evaluate changes in functional images (MRI, Perfusion - CT, & FDG PET) after treatment with chemoradiotherapy.

NuTide301

This is a two part, Phase 1 open label dose escalation and expansion study to assess safety, pharmacokinetics and clinical activity of NUC-3373, a nucleotide analogue, in participants with advanced solid tumours.

CYTOFLOC

MONITOR

MONITOR PsA - Multicentre ObservatioNal Initiative in Treat to target Outcomes in Psoriatic Arthritis

MACRO

This NIHR Programme aims to provide high quality evidence to establish best practice for the management of this common sinus disease. The large multi-disciplinary MACRO research team have come together to tackle the disease from many different aspects – across primary and secondary care, and from a clinical, economic and patient perspective