Search results

PROMOTE IR800 IAB2M (Stage 2)

This is a single-centre study in those with high-risk prostate cancer.

OCTO-ART

This is a single centre observational study to evaluate changes in functional images (MRI, Perfusion - CT, & FDG PET) after treatment with chemoradiotherapy.

NuTide301

This is a two part, Phase 1 open label dose escalation and expansion study to assess safety, pharmacokinetics and clinical activity of NUC-3373, a nucleotide analogue, in participants with advanced solid tumours.

CYTOFLOC

MONITOR

MONITOR PsA - Multicentre ObservatioNal Initiative in Treat to target Outcomes in Psoriatic Arthritis

MACRO

This NIHR Programme aims to provide high quality evidence to establish best practice for the management of this common sinus disease. The large multi-disciplinary MACRO research team have come together to tackle the disease from many different aspects – across primary and secondary care, and from a clinical, economic and patient perspective

CHARIOT

This is a multi-centre, open label, 2 stage trial in patients with oesophageal cancer

TWO

This is a study to assess cell therapy as a treatment to prevent kidney transplant rejection. Patients will be randomly assigned to either receive standard medication after transplant or a modified regimen including the cell product.

PEP-TALK

CEDAR

CEDAR: Chemoradiation with Enadenotucirev as a radiosensitiser in locally advanced colorectal cancer

DOC-MEK

This is a multi-centre randomised trial of docetaxel with or without AZD6244 in advanced melanoma

PART

The PART study is a feasibility study comparing partial ablation (PA) and radical prostatectomy (RP) in men with intermediate risk unilateral prostate cancer. The aim of the feasibility is to determine whether or not it is possible to recruit and randomise men to a trial of this nature.

POISE

Clinical effectiveness of symptomatic therapy compared to standard step up care for the treatment of low impact psoriatic oligoarthritis: a 2 arm parallel group feasibility study

STARR2

Delivering personalised care in the management of exacerbations of chronic obstructive pulmonary disease: A multi-centre randomised clinical trial.

REGENERATE

This is a multi-centre, non-randomised trial of gene therapy in those with the condition choroideremia.

HOME

How can we best address prolonged hospital stays in older inpatients with medical-psychiatric multimorbidity?

OTTER-2

A randomised controlled trial into the effectiveness and efficacy of splints in thumb based osteoarthritis.

PReSuTINeB

A randomized placebo-controlled study in patients with neurogenic bladder dysfunction and recurrent urinary tract infections (UTIs)

ATOM

This pre-operative window of opportunity study will use functional imaging and serological investigations to assess whether atovaquone significantly reduces tumour hypoxia in patients with non-small cell lung cancer.

IMAGO

A single arm exploratory study examining the feasibility of imaging glioblastoma pH using CEST MRI