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The Aspirin Esomeprazole Chemoprevention Trial (AspECT) is to our knowledge one of the largest cancer prevention trials using aspirin and acid suppression in the world. In total 2557 patients with a common precancerous change in their oesophagus, called Barrett’s oesophagus, were followed up for an average of 9 years resulting in over 20,000 life-years of follow up. After informed written consent, patients were randomly allocated to four different combinations; Low acid suppression alone, High acid suppression alone, low acid suppression with 300mg aspirin and high acid suppression with 300mg aspirin. We wanted to see if we could prevent progression to local cancer/cancer in-situ (high grade dysplasia), invasive cancer or prevent death by all causes both cancer and non-cancer.
IT Analyst (172818)
NDORMS Professional services
This role involves being the initial point of contact for all technical inquiries and issues, ensuring prompt and effective resolution to maintain uninterrupted research operations.
Postdoctoral Researcher in Biomaterials and Bioreactors for Tissue Engineering (172551)
Botnar Research scientists
We are looking for an experienced, uniquely skilled and highly motivated postdoctoral researcher to join a research team working on the development of biomaterials and bioreactors for soft tissue repair applications.
Research Nurse (Part-Time) (172783)
NDORMS Research delivery
We have an exciting opportunity for a Research Nurse to join our small, friendly research team working within a multi-disciplinary setting between rheumatology, orthopaedics and physiotherapy.
Programme Manager for Functional Genomics Cluster (Part-Time) (172807)
Botnar Professional services
As a Programme Manager you will be an integral part of our team and you will manage all non-academic administration functions for the Centre which covers research spanning basic genetics, bioinformatics and AI, through functional genomic readouts and tissue imaging, to human tissue models, organoids, and bioreactors.
Laboratory Technician in Next Generation Sequencing of Musculoskeletal Tissues (172220)
Botnar Research delivery
We seek an experienced and enthusiastic individual to join the Cribbs and Snelling labs and work within the UK Research and Innovation Musculoskeletal Functional Genomics Cluster. Your work will help to accelerate translation of genetic findings to treat four key musculoskeletal diseases: osteoarthritis, carpal tunnel syndrome, frozen shoulder, and Dupuytren disease.