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The Aspirin Esomeprazole Chemoprevention Trial (AspECT) is to our knowledge one of the largest cancer prevention trials using aspirin and acid suppression in the world. In total 2557 patients with a common precancerous change in their oesophagus, called Barrett’s oesophagus, were followed up for an average of 9 years resulting in over 20,000 life-years of follow up. After informed written consent, patients were randomly allocated to four different combinations; Low acid suppression alone, High acid suppression alone, low acid suppression with 300mg aspirin and high acid suppression with 300mg aspirin. We wanted to see if we could prevent progression to local cancer/cancer in-situ (high grade dysplasia), invasive cancer or prevent death by all causes both cancer and non-cancer.
Botnar DPhil & MSc by Research
NDORMS provides excellent opportunities for high quality research training in leading areas of musculoskeletal and inflammatory sciences and an outstanding environment for undertaking a DPhil, Oxford’s equivalent to a PhD.
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Black History Month 2020
Oxford University welcomes Black History Month. Throughout October events and content streams will run University-wide, across colleges, departments and divisions.
UNIQ+ Summer School 2019
UNIQ+ Postgraduate Summer School now accepting applications
10th NIHR OTS Musculoskeletal Trauma Trials Annual Meeting
This event is run by the Orthopaedic Trauma Society and the National Institute for Health and Care Research with support from Clockwork Medical. To register, please click on the link below.
Cemented or Uncemented Hemiarthroplasty for Intracapsular Hip Fracture
Paper published in The New England Journal of Medicine.
LGBT+ History Month
February is LGBT+ History Month and the University is organising a series of events.
Bristol Oxford Surgical Trials Intervention Course (BOSTiC)
New dates are to be announced soon for BOSTiC 2022. Please email situ@ndorms.ox.ac.uk to add your name to the waiting list and be informed as soon as delegates are able to register.
Read our latest study
Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines)