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By changing mouse genes to block a protein associated with obesity, researchers at the Kennedy Institute of Rheumatology, NDORMS have prevented fat from forming around the animals' internal organs, even when the animals eat an unhealthy diet. The study in Nature Medicine found that these genetically engineered mice also retained their sensitivity to insulin (normally blunted by obesity), despite gaining weight.
Clinical Kennedy Trust Prize Studentships
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Botnar projects
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Themes
OCTRU runs trials across multiple areas of medicine. Within OCTRU there are five core therapeutic areas of expertise, although trials are also undertaken outside of these areas and groups.