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Spondyloarthritis encompasses a group of common inflammatory diseases caused by an overactive immune response affecting up to half a million people in the UK alone.

Model for role of GM-CSF in spondyloarthritis chronic inflammation. GM-CSF is produced by joint-resident innate lymphoid cell (ILC) and infiltrating CD4 T cells and acts to activate monocytes to produce other molecules that propagate the inflammatory response.
Model for role of GM-CSF in spondyloarthritis chronic inflammation. GM-CSF is produced by joint-resident innate lymphoid cell (ILC) and infiltrating CD4 T cells and acts to activate monocytes to produce other molecules that propagate the inflammatory response.

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