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A clinical trial to test a new treatment for Dupuytren’s disease has commenced at the Kennedy Institute and Botnar Research Centre. Affecting 4% of the UK population, this disease causes fingers to curl into the palm and can be extremely disabling.
Nirmatrelvir-ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022-23: virological and immunological results of an open-label randomised trial (PANORAMIC).
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Lowe DM. et al, (2027), Lancet Microbe
Multi-objective optimisation of 3D-printed multilayer TPMS osteochondral scaffolds for enhanced mechanical and biological performance
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Xu Y. et al, (2026), Virtual and Physical Prototyping, 21
Subharmonics are not an infallible safety metric for cavitation dynamics.
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Wu Q. et al, (2026), Int J Hyperthermia, 43
Assessing the Importance of Variation in Diagnostic Coding Among the Three Countries in the UK Biobank
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Clifton L. et al, (2026), Learning Health Systems, 10
Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL
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Coates LC. et al, (2026), RMD Open, 20, e043855 - e043855
Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature.
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Scherlinger M. et al, (2026), J Transl Autoimmun, 12
Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023).
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Perletta V. et al, (2026), ESMO Real World Data Digit Oncol, 12
Recent advances in biomaterials and structural design of 3D printed multiphasic scaffolds for osteochondral regeneration
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Xu Y. et al, (2026), Materials Science and Engineering: R: Reports, 170, 101210 - 101210
Ikaros degradation by mezigdomide reduces T-cell dysfunction and improves the efficacy of antimyeloma T-cell therapies.
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Chen LY. et al, (2026), Blood
Losartan and Prednisolone for Post-COVID Syndrome and Cardiac Inflammation: A Randomized, Double-Blind, Placebo-Controlled Trial
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Puntmann VO. et al, (2026), Nature Communications
Volumetric Additive Manufacturing of Embedded Channels for Studying Flow and Permeation in Hydrogel Systems
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Stride E., (2026), Advanced Materials Technologies
Hedgehog Inhibitor and Paclitaxel: A Phase I Trial of the Oral Hedgehog inhibitor Taladegib in Combination with Weekly Paclitaxel in Patients with Advanced Solid Tumours.
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Glasspool R. et al, (2026), Invest New Drugs
Identification of genetic risk loci associated with aquaporin 4-positive neuromyelitis optica spectrum disorder: a genome-wide association study.
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Attfield KE. et al, (2026), Lancet Neurol, 25, 482 - 491
Deformation-Recovery diffusion model (DRDM): Instance deformation for image manipulation and synthesis.
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Zheng J-Q. et al, (2026), Med Image Anal, 110
The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care.
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Sharma A. et al, (2026), BJU Int, 137, 849 - 857
Identifying the Initiation of a New Line of Therapy for Metastatic Lung, Breast, and Colorectal Cancer in Real-World Data: A Scoping Review.
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Onasanya O. et al, (2026), Pharmacoepidemiol Drug Saf, 35
Reoperation in the year following a hip fracture : a nationwide cohort study in England.
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Patel R. et al, (2026), Bone Joint J, 108-B, 698 - 706
Age and symptom severity as predictors of outcomes following shockwave therapy in Achilles tendinopathy : a single-centre observational study.
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Hutchison A-M. et al, (2026), Bone Joint J, 108-B, 650 - 656
Medium-term recovery of patients with complex lower limb fractures : follow-up study of fracture types in the Wound Healing in Surgery for Trauma (WHIST) trial.
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Goh EL. et al, (2026), Bone Joint J, 108-B, 681 - 687
Microbubbles manufactured using a tissue homogeniser: DoE-guided optimisation for a narrower size distribution and higher yield.
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O'Reilly CS. et al, (2026), Int J Pharm