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The HTA has funded the CORKA Trial - a RCT to investigate rehabilitation after joint replacement of the knee for chronic arthropathy. Work on the trial has officially started today and further information on the trial and its progress will be available soon on the OCTRU Current Projects Page.
New centre aims to help companies conduct more efficient trials
Botnar Main Trials
26 February 2021
A new clinical therapeutics centre has been set up by the University of Oxford to help life sciences companies identify interventions that have the greatest potential to deliver patient benefit, and so bring down the cost of early phase clinical trials.
Cognitive–behavioural therapy consistently improves quality of life
Main Rehabilitation and self-management Research
26 February 2021
A meta-review of the available research into cognitive behavioural therapy reveals it consistently improves health-related quality of life across different medical conditions and demographic populations.
Oxford to collaborate with Janssen to map the cellular landscape of immune mediated disorders
Main Research
19 February 2021
The University of Oxford has entered into a strategic collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.
Versus Arthritis Foundation Fellowship awarded to Dr Kristina Zec
Awards Main
19 February 2021
Dr Kristina Zec has been awarded a Versus Arthritis Foundation Fellowship to investigate the role of products of lipid oxidation produced by synovial macrophages in triggering articular inflammation.
Study reveals the safety of bisphosphonates in chronic kidney disease
Main
10 February 2021
The results of an observational study published in JMBR and funded by the Health Technology Assessment Programme shows that bisphosphonate use is associated with a greater risk of chronic kidney disease progression.
WHiTE Four trial results published
Hip Main OCTRU Orthopaedics and trauma Research
9 February 2021
The results of the WHiTE Four clinical trial for the treatment of fragility hip fractures have been published in The Bone and Joint Journal.
Vascular loss shown to be the primary hallmark of aging
Kennedy Main Tissue remodelling and regeneration
4 February 2021
New Research from the Kusumbe group at the Kennedy Institute of Rheumatology identifies vascular attrition, marked by pericyte to fibroblast differentiation, as a primary hallmark of aging and highlights organ-specific vascular changes with age.
Understanding the first wave of COVID-19 and implications for tackling the ongoing pandemic: evidence from 5.5 million people from Catalonia, Spain
Botnar Main Research Statistics and epidemiology
3 February 2021
Health outcomes during the first wave of COVID-19 in Catalonia, Spain, have been described in detail in a study published by Nature Communications.
New Capture the Fracture policy guidance highlights global need for post-fracture care programs
Main Orthopaedics and trauma
2 February 2021
‘Capture the Fracture® (CTF) Partnership – Guidance for Policy Shaping’ sets out a step-by-step approach to building secondary fracture prevention policy which can improve patient outcomes, save healthcare costs, and save lives.
Immunology preprint reviews launched in Nature Reviews Immunology
Kennedy Main Research
15 January 2021
The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.
A more tailored approach to treating psoriatic arthritis
Arthritis Botnar Funding Main
8 January 2021
Dr Laura Coates has been awarded £1.8M from the National Institute for Health Research (NIHR) to explore the potential for precision medicine in the choice of biologics to reduce inflammation and pain in psoriatic arthritis.
Motion-capture to help children walk: Oxford team support new gait laboratory in Ethiopia
Main Orthopaedics and trauma
7 January 2021
The Research at Oxford on Analysis of Motion (ROAM) team at the University of Oxford have supported CURE Ethiopia Children’s Hospital to develop and open a brand new gait laboratory, the first of its kind in the country and the only other active gait lab on the African continent outside of South Africa.
Professor Eleanor Stride recognised in New Year’s Honours list 2021
Awards Main
4 January 2021
Statutory Professor of Biomaterials is awarded Officer of the Order of the British Empire (OBE) for services to Engineering
Drug may boost vaccine responses in older adults
Kennedy Main
18 December 2020
A preliminary study shows that a drug which helps immune cells self-clean may improve vaccine protection in older adults
Living reviews launched by Oxford and Cardiff in the wake of COVID-19 research
Kennedy Main Research
18 December 2020
In a combined effort to help COVID-19 researchers the University of Oxford and Cardiff University have launched a series of “living reviews” in Oxford University Press’s new open access journal “Oxford Open Immunology”.
Oxford University awarded £2.4 million to fund DPhil research in inflammation, immunology and musculoskeletal disease
Awards Inflammation biology Kennedy Main
18 December 2020
Oxford University has today been awarded a £2.4 million grant, as part of the Kennedy Trust MB PhD scheme, to fund undergraduate medical students to undertake DPhil research in the areas of inflammation, immunology and musculoskeletal disease.
Plastic surgeons recommend a review of cancer excision guidelines after finding variations in effectiveness
Main Oncology
15 December 2020
A systematic review finds Incomplete excision rates for basal cell carcinoma range from 4.7% to 20.4% against recommended guidelines of 5%.
3D imaging reveals the role of blood vessels in hormone production
Kennedy Main Research
11 December 2020
New research from the Kusumbe Group at the Kennedy Institute has shown a direct correlation between age-related decline in capillary and artery numbers and hormone production in the endocrine system.
£3M invested to drive forward early translation through five new Oxford-Bristol Myers Squibb Fellowships
Awards Kennedy Main
10 December 2020
Five new Oxford-Bristol Myers Squibb Fellowships representing an investment of £3M have been announced. The fellowships (formerly Oxford-Celgene) will support postdoctoral researchers and clinicians across five departments within the Medical Sciences Division and the Mathematical, Physical and Life Sciences Division, providing an opportunity for them to gain exposure to the field of commercial drug discovery and development.
NDORMS researcher receives an MRC Career Development Award
Awards Botnar Main
4 December 2020
Adam Cribbs has been awarded a prestigious MRC Career Development Award to further his research to identify therapeutic targets for multiple myeloma.