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The HTA has funded the CORKA Trial - a RCT to investigate rehabilitation after joint replacement of the knee for chronic arthropathy. Work on the trial has officially started today and further information on the trial and its progress will be available soon on the OCTRU Current Projects Page.
New insights into chronic inflammation in rheumatoid arthritis
30 June 2025
Kennedy researchers have uncovered new clues about how immune memory exacerbates inflammation in rheumatoid arthritis, which could lead to better ways to control the disease.
‘Single shot’ malaria vaccine delivery system could transform global immunisation
26 June 2025
Oxford researchers have developed programmable microcapsules to deliver vaccines in stages, potentially eliminating the need for booster shots and increasing immunisation coverage in hard-to-reach communities.
Dr Chrissy Bolton wins Best Abstract Award at EULAR 2025 Congress
25 June 2025
Kennedy DPhil student Chrissy Bolton has been awarded Best Abstract in Basic and Translational Science at the European Alliance of Associations for Rheumatology 2025 (EULAR) conference.
£1.4m awarded to investigate how tumour mechanics affect the immune response to cancer
24 June 2025
Professor Marco Fritzsche from the Kennedy Institute of Rheumatology, is co-leading a research project that has been awarded a £1.4 million Programme Foundation Award from Cancer Research UK, to investigate how physical forces within tumours affect the ability of a type of white blood cell to attack and eliminate cancer cells.
Associate Professor reaches new heights with the Thames Valley Air Ambulance
23 June 2025
David Metcalfe, Associate Professor of Emergency Medicine at NDORMS, has begun a two-year secondment with Thames Valley Air Ambulance.
Designing better bispecific T-cell engagers for cancer immunotherapy
19 June 2025
Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs) - a class of cancer immunotherapy drugs. The findings may help unlock the full potential of TcEs and revolutionise cancer treatment for patients.
Versus Arthritis invests in ‘team science’ to meet pressing challenges faced by people with arthritis
17 June 2025
Researchers at the Botnar Institute have joined a new consortium that has been awarded £3m from the charity Versus Arthritis to bring world-leading experts from five UK universities together to accelerate clinical epidemiology research, which will help answer pressing questions from those living with arthritis.
NDORMS researchers awarded Associate Professor title
16 June 2025
Ghada Alsaleh and Alex Clarke have been awarded the title of Associate Professor by the University of Oxford.
Professor Andrew Carr recognised in King’s Birthday Honours
14 June 2025
Professor Andrew Carr was honoured in the 2025 King’s Birthday Honours List being awarded an MBE for services to Orthopaedic Research and Training.
NDORMS researchers search for the ‘achilles heel’ of chondrosarcoma
12 June 2025
A new study to better understand the deadly bone cancer chondrosarcoma aims to reveal potential 'weak spots' of the disease with the ultimate goal of developing more effective treatments for patients.
Psoriatic arthritis: hit hard and early
11 June 2025
Laura Coates presents the results from the 'SPEED' trial that found early use of biologic therapy or combination conventional DMARDs may be more effective than standard step-up care with methotrexate for psoriatic arthritis patients with poor prognostic factors.
New research identifies key driver of inflammation in spondyloarthritis
5 June 2025
NDORMS researchers have identified a primary source of inflammatory IL-17 driving spondyloarthritis, paving the way for the development of targeted therapies to treat the condition.
David Keene appointed to Kadoorie Professorship of Trauma Rehabilitation
2 June 2025
David Keene will lead advanced research and teaching in trauma rehabilitation at Oxford Trauma and Emergency Care within NDORMS.
New NDORMS study looking for a breakthrough in osteosarcoma
28 May 2025
The Bone Cancer Research Trust and Sarcoma UK are joining forces to launch two groundbreaking research projects which could support the early diagnosis of primary bone cancer.
Professor Amar Rangan announced as new Fellow of the Academy of Medical Sciences
23 May 2025
Professor of Orthopaedic Surgery Amar Rangan has been recognised as an exceptional health scientist in his election as a Fellow of the Academy of Medical Sciences.
Speedy diagnosis and treatment are key for wrist injury patients
19 May 2025
A new study supports the strategy of using early MRI scans to significantly improve care and experiences for patients with wrist injuries.
NDORMS researchers deliver pioneering treatment for rare genetic condition
15 May 2025
A team at NDORMS, University of Oxford has successfully administered a pioneering treatment to a patient with XIAP deficiency, a rare genetic disorder.
TCRs drive CARs
1 May 2025
Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer treatments. This study, published in Cell, demonstrates that engineering T-cells to express both a Chimeric Antigen Receptor (CAR) and a T-cell Receptor (TCR) can improve their ability to distinguish between cancerous and healthy tissues—addressing a major challenge in current immunotherapy.
Common virus may improve skin cancer treatment outcomes, study finds
25 April 2025
A new study led by the University of Oxford has revealed that a common and usually harmless virus may positively influence how skin cancer patients respond to current treatments.
CRUK funding for research into earlier detection of relapse in people with multiple myeloma
23 April 2025
Dr Karthik Ramasamy and team will assess a new mass spectrometry-based monitoring technique for its ability to predict and identify early disease relapse.