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February marks the 75th anniversary of the first therapeutic dose of penicillin given to a patient in 1941 at Briscoe Ward, Radcliffe Infirmary.
We develop statistical methods and computational software to better understand the genetic contribution to immune-mediated traits.
Applying multi-omic and computational genomic approaches to understand the molecular basis of host-microbiome interactions
Cerebral palsy is the most common cause of childhood disability. The Theologis Group will run the first ever set of trials into cerebral palsy, to address the issues that matter the most to patients and provide evidence-based solutions.
PRePPeD – Physiotherapy Rehabilitation Post Patellar Dislocation
This trial aims to compare two treatment methods that are currently standard care for treating wrist fractures. There are a large number of wrist fractures every year in the UK and by comparing the clinical and cost effectiveness of the treatments, this could help save money for the NHS.
Imaging in Paediatric Osteomyelitis (the PICBONE study): a multi-centre cohort study to understand the role of MRI and ultrasound in the diagnosis of acute haematogenous osteomyelitis in children
Tailored Exercise Management for People aged 80 years or older with hip/knee Osteoarthritis: a feasibility randomised trial.
Hand Osteoarthritis: investigating Pain trajectories and association with biomarkers including Estrogen cohort (HOPE-c)
Arthritis Botnar Hand
Ecological Momentary Computerised Adaptive Testing
Inflammation biology Kennedy
We aim to uncover the stromal basis of chronic inflammation and related tissue pathology to target fibroblasts across a range of immune-mediated inflammatory diseases.
The HAWAII Feasibility Study: A multi-centre randomised feasibility study to determine the key indicators of feasibility for a definitive trial of antimicrobial sutures versus standard sutures in hand and wrist trauma surgery in adults aged 18 years old and over.
Botnar Statistics and epidemiology
Retinoic acid metabolism blocking agents to treat osteoarthritis of the hand: A 2-arm double-blind randomised controlled proof of concept study (RAMBOH-1)