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New research at the Kennedy Institute reveals potential of a novel class of drugs for the treatment of rheumatoid arthritis.

cIAP inhibitors restore a healthy balance between inflammatory and regulatory T lymphocytes to reduce inflammatory arthritis

Methods for the development and validation of computable phenotypes based on biobanks and linked real world data

Deadline - Friday 15 May 2026

Measuring the mathematical similarity and distance between real-world databases and their transformation into Common Data Models: an OMOP case study to strengthen data quality in observational research

Artificial Intelligence for musculoskeletal global health

People Powered Research – Investigating ethical and operational hurdles in public-research engagement

Assessing the use of treatments for blood cancers using real world data

Fibrosis across musculoskeletal tissues: Comparison of resolving and persistent fibrotic niches

Pro-resolving therapies: A new therapeutic paradigm targeting inflammation in equine tendon injury

Advanced Analysis of 15-Year Outcomes in the Arterial Revascularization Trial: Implications for CABG Strategies

Modelling recovery after common hand surgery procedures

Emulating and extending randomised controlled trials using routinely-collected data from Europe

Large language models for phenotyping in Real World Evidence distributed analytics: bridging expert knowledge and artificial intelligence

Improving the quality of real world evidence by measuring and minimising outcome misclassification using the OMOP common data model and large multinational health data

Osteogenic-angiogenic coupling in fracture repair - Why do some patients fail to heal?

Investigating pro-inflammatory vs pro-remission mechanisms across immune disorders: integrating single-cell/spatial multiomics & ML/AI approaches for patient-level translational insights

Investigating pro-inflammatory vs pro-remission mechanisms across immune disorders: integrating single-cell/spatial multiomics & ML/AI approaches for patient-level translational insights

Multi-dimensional analysis of the immunological synapse in the context of immunotherapy

Virtual Immune Cells – Combing Mechanism, Genomics & AI to Predict T cell responses

Multi-dimensional analysis of the immunological synapse in the context of immunotherapy

Multi-dimensional analysis of the immunological synapse in the context of immunotherapy

Integrated Ultrasound-Enhanced Biophotonic Platform for High-Throughput Studies of Cancer–Immune Cell Mechanobiology

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Meet the team

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cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs

Scientific Advances 2019

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Two targets are better than one 

Nature Reviews Rheumatology

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Anti-TNF Drugs

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NDORMS hosts international workshop to advance therapeutic discovery in chondrosarcoma

Researchers, clinicians, industry partners, bone cancer charities and patients recently gathered at St Catherine’s College, University of Oxford, for the inaugural ‘Oxford Workshop on Systems Biology and Therapeutic Approaches in Chondrosarcoma’. The event brought together expertise across research and clinical care with the long-term aim to improve outcomes for patients with chondrosarcoma.

New research programme to strengthen the evaluation of implants in the NHS

Associate Professor title awarded to NDORMS researchers

James Fullerton appointed as John Climax Professor of Clinical Therapeutics

Large UK trial shows bone healing ‘superpower’ in children

£3M study led by patient voices targets pain in inflammatory arthritis