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Neutralising mAbs, a form of anti-viral medicine, are being explored as an attractive option to treat symptoms of COVID-19 and in some cases prevent infection. But what are the pros and cons of this type of treatment and what should regulators consider before granting approval?
New study sheds light on the debate surrounding two types of shoulder replacement surgery for osteoarthritis
Botnar Main Shoulder
1 May 2024
A new study has provided valuable insights into the ongoing debate surrounding two types of shoulder replacement surgery: reverse total shoulder replacement and anatomical total shoulder replacement as a treatment for patients with osteoarthritis.
NHS baby check may miss dislocated hips in new-born babies
Botnar Hip Main
25 April 2024
A new study has identified that NHS infant checks can miss serious hip abnormalities in new-born babies. Left undetected, these can require complex surgery, and lead to early arthritis. In the UK around 500 infants undergo surgery for dislocated hips which could have been avoidable.
New Study uses AI to predict malaria outbreaks in South Asia
Botnar Main
23 April 2024
Researchers from NDORMS in collaboration with international institutions have demonstrated the potential of using environmental measurements and deep learning modeling to predict malaria outbreaks in South Asia. The study offers promising insights into improving early warning systems for one of the world's deadliest diseases.
HIPCARE trial launches in the Philippines
Main Orthopaedics and trauma Trials
22 April 2024
Prof Matt Costa has just returned from the Philippines, where he launched the new HIPCARE trial with co-lead investigator Prof Irewin Tabu. The first of five Low- and Middle-Income Countries (LMIC) in Asia to take part, eight hospitals in the Philippines will start recruiting patients with fragility fractures of the hip to the study within weeks.
Justin Wormald wins NIHR awards and takes up position as SITU Deputy Director
Awards Main SITU
17 April 2024
NDORMS alumnus Justin Wormald has been awarded an NIHR Academic Clinical Lectureship and an NIHR Development and Skills Enhancement (DSE) Award, as well as being appointed as Deputy Director of the Surgical Trials Intervention Unit (SITU-NDORMS).
New TRIPOD+AI guidelines reflect growing use of AI in healthcare research
Botnar CSM Main
16 April 2024
The widespread use of artificial intelligence (AI) in medical decision-making tools has led to an update of the TRIPOD guidelines for reporting clinical prediction models. The new TRIPOD+AI guidelines are launched in the BMJ today.
COVID-19 vaccines effectiveness: results from Norway demonstrate the reproducibility of federated analytics
Botnar Coronavirus COVID-19 Main Statistics and epidemiology
11 April 2024
Researchers from NDORMS and the University of Oslo, have successfully replicated findings from recently published international studies on the effectiveness of COVID-19 vaccines to prevent long COVID and post-acute complications.
Connects-UK launches to foster scientific collaborations between EU and UK researchers in a post-Brexit era
Kennedy Main Research
10 April 2024
Connects-UK, a new pan-European network dedicated to advancing scientific collaborations between researchers in the European Union (EU) and the United Kingdom (UK), was officially launched at an event in London yesterday. The network, led by a diaspora of EU researchers working in the UK, seeks to bridge the gap created by Brexit and ensure that collaboration, innovative research, funding, and knowledge exchange continue to thrive in the post-Brexit era.
New study reveals how T cells gain and maintain tolerance to gut bacteria
Inflammation biology Kennedy Main Research
4 April 2024
The immune system in the intestine maintains a careful balance, tolerating our long-term resident (commensal) gut bacteria while defending against invading pathogens. Under certain circumstances, dysregulation of our intestinal immune response to commensal and pathogenic microbes can drive inflammatory disease.
Simon Matthew Graham awarded an MRC Clinician Scientist Fellowship
Botnar Funding Main Orthopaedics and trauma
26 March 2024
The award from the Medical Research Council (MRC) will support research to improve treatments for open fractures in low- and middle-income countries.
New framework guides the use of AI for clinical diagnosis
Botnar Main Research
25 March 2024
NDORMS researchers have conducted a review of the literature on the use of AI in clinical decision-making. Published in the Lancet the study identifies why AI has not yet been taken up more widely, and provides a framework to better inform future adoption and integration of the technology.
New study reveals long-term mental health risks after COVID-19
Botnar Coronavirus COVID-19 Main Statistics and epidemiology
21 March 2024
A new study published in Nature Human Behaviour sheds light on the long-term mental health consequences of COVID-19 infection and the growing evidence of the protective effect of vaccination on reducing the risk.
NDORMS’ Athena Swan Silver award renewed
Awards Equality and diversity Main
20 March 2024
NDORMS has been awarded the Athena Swan Silver award for the third consecutive time, recognising the department’s commitment to gender equality.
AI Software yields six-fold increase in spine fracture identification
Botnar Main
19 March 2024
Early findings in the ADOPT study, show that Nanox.AI software improves the detection of spine fractures, an early sign of osteoporosis, outperforming UK National Health Service national average.
Professor Gary Collins awarded prestigious NIHR Senior Investigator award
Awards Botnar CSM Department General Main
15 March 2024
NDORMS Professor of Medical Statistics and Director of the Centre for Statistics in Medicine, Gary Collins has been appointed National Institute of Health Research (NIHR) Senior Investigator.
New bronchoscopy capability expands capacity for respiratory and vaccine trials
Botnar Main Trials
14 March 2024
The NIHR Oxford Clinical Research Facility (EMCRF) hosted by NDORMS has expanded its capability to undertake research bronchoscopies. The facility welcomed its first volunteers as part of the Oxford Airways Study to help understand the causes of asthma.
COVID jab linked to lower risk of COVID-19-related clot and heart complications
Botnar Main Statistics and epidemiology
13 March 2024
NDORMS research shows that vaccination reduced the risk of heart failure and some clot-related complications for up to a year.
PD-1 gets an “A” for team-work
Kennedy Main
8 March 2024
A new understanding of the PD-1 axis (programmed death cell) could help shape ongoing efforts to improve treatments for cancer and autoimmune diseases.
Professor Irina Udalova appointed to the MRC’s Infections and Immunity Board
Kennedy Main
1 March 2024
The Medical Research Council’s Infections and Immunity Board (IIB) funds research into infectious human disease and disorders of the human immune system.