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Mark Coles receives funding to tackle viral threats

Professor Mark Coles is leading one of three innovative University of Oxford research projects that have secured funding through the UK's Advanced Research and Invention Agency (ARIA) to transform how we protect against respiratory viruses.

Natural compound may help boost vaccine responses in older adults

NDORMS researchers have found that a naturally occurring compound called spermidine may help improve vaccine responses in some older adults by reducing signs of immune system ageing.

Pioneering study sets out to answer and address why osteoarthritis impacts patients differently

Researchers from NDORMS are playing leading roles in a major new UK-wide research consortium aiming to improve treatment and outcomes for people living with osteoarthritis.

Largest study of knee osteoarthritis tissue reveals the core biological pathways underlying osteoarthritis

A major international study led by researchers at the Kennedy Institute of Rheumatology at the University of Oxford has found that osteoarthritis (OA) – the most common form of arthritis worldwide – is not a collection of separate diseases, as many scientists had previously speculated, but rather a single condition with common core underlying biological pathways.

£3M study led by patient voices targets pain in inflammatory arthritis

Researchers across the UK are banding together to tackle one of the largest unmet clinical needs in inflammatory arthritis, pain reduction, in a new £3m research programme funded by Arthritis UK.

Oxford–ZEISS Centre to advance live-cell imaging for drug discovery

The pioneering technology will be able to precisely quantify drug behaviour at the cellular level for the development of novel therapeutics.

Kennedy Institute of Rheumatology secures five-year major funding from the Kennedy Trust for Rheumatology Research

The Kennedy Institute of Rheumatology (KIR) at the University of Oxford has secured a major five-year funding commitment of £28 million from the Kennedy Trust for Rheumatology Research (KTRR), extending its long-standing strategic partnership to 2031.

Anchoring a key immune molecule boosts T cell responses

Researchers at the Kennedy Institute of Rheumatology have found that physically resisting the formation of an immunological synapse actually promotes a stronger immune response. The findings could help explain how immune responses become weakened in cancer and chronic infection and inform the design of more effective vaccines.

Kennedy scientists join world-leading researchers in ‘pivotal’ study to help arthritis patients to live drug free

The prospect of long-lasting drug-free remission for children and adults living with inflammatory arthritis is a step closer to becoming a reality, thanks to a new collaboration.

What determines the fate of a T cell?

Research led by Dr Mariana Borsa at the Kennedy Institute has found that a cellular housekeeping mechanism called autophagy plays a major role in ensuring that T cells generate diverse progenies upon cell division. The findings, published in Nature Cell Biology, could help boost vaccine response in older adults.

Kennedy researchers contribute to UK-wide AI and bioscience training initiative

Together with a group of Oxford researchers, Mark Coles, Professor of Immunology at the Kennedy Institute, will co-lead the Enabling Next-generation AI for a Bioscience-Led Economy (ENAIBLE) initiative.

World-leading researchers unite for ‘pivotal’ study to help children and adults with arthritis to live drug free

The prospect of long-lasting drug-free remission for children and adults living with inflammatory arthritis is a step closer to becoming a reality, thanks to a new collaboration which includes world-leading researchers from the Kennedy Institute.

Two NDORMS groups join the PROBE Initiative to advance osteoarthritis research

Two research groups at NDORMS have joined the newly launched PROBE initiative, contributing their expertise to a major European collaboration focused on improving the understanding, diagnosis and treatment of osteoarthritis.

Oxford and GSK launch Experimental Medicine Collaboration

GSK invests £10 million over five years to establish the Experimental Medicine Collaboration with the University of Oxford.

Shaping immunity - the secrets behind the shape of neutrophils

Researchers at the Kennedy Institute have provided the most comprehensive overview to date of how the distinctive segmented nucleus of neutrophils influences their function in health and disease.

Oxford researchers to redefine new human-based research models of pain

Professor Tonia Vincent is part of an interdisciplinary team from Oxford University leading a major new initiative which aims to redefine human-based research models for greater understanding of disease and the acceleration of new medicines.

New Microbiome Innovation Network to drive UK Bioscience Research

Researchers from the Kennedy Institute are part of a UK-wide consortium that has been awarded a £644K BBSRC Network Grant to establish the Microbiome Innovation Network (Microbiome-Net).

NDORMS recognised as a European Centre of Excellence

NDORMS has been awarded the designation of a EULAR Centre of Excellence for a third consecutive term. This prestigious award is a recognition of the department’s contribution to advancing the science of rheumatic and musculoskeletal diseases.

First of its kind study for children with arthritis reveals possible new disease targets

Researchers have been able to see what happens in the inflamed joints of children with arthritis, giving insight into why treatments affect children differently.

New insights into chronic inflammation in rheumatoid arthritis

Kennedy researchers have uncovered new clues about how immune memory exacerbates inflammation in rheumatoid arthritis, which could lead to better ways to control the disease.

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