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FRUITI

• OCTRU
• Oxford Trauma

World Hip Trauma Evaluation - FRUITI: Fix or Replace Undisplaced Intracapsular fractures Trial of Interventions

PROCURE

• OCTRU
• SITU

Partial Rotator Cuff Tear Repair Trial (PRO CURE Trial)

PART

• OCTRU
• SITU

A randomised controlled trial of Partial prostate Ablation versus Radical Treatment in intermediate risk, unilateral clinically localised prostate cancer

NEON

• OCTRU
• SITU

Repair of digital nerve injury

HUSH

• OCTRU
• Oxford Trauma

The HUmeral SHaft fracture trial

CPinBOSS Study

• Botnar
• SITU
• Trials

CPinBOSS - Cerebral Palsy in the British Orthopaedic Surgery Surveillance Study

CRAFFT

• OCTRU
• Oxford Trauma

Children’s Radius Acute Fracture Fixation Trial. A multi-centre prospective randomized non- inferiority trial of surgical reduction versus non-surgical casting for displaced distal radius fractures in children.

WAX

• OCTRU
• Oxford Trauma

Weight-bearing in Ankle Fractures

GRRAND-F

• OCTRU
• RRIO

Dakin Group | Soft Tissue Joint Disease

• Botnar
• Inflammation biology
• Orthopaedics and trauma
• Tissue remodelling and regeneration

The Dakin Group undertakes translational research focusing on identifying the cellular and molecular basis of inflammatory fibrotic soft tissue joint diseases, with research programmes on tendinopathy, frozen shoulder and knee arthrofibrosis. Understanding the cellular and molecular basis of these diseases will inform new therapeutic approaches targeting tissue resident stromal cells of the joint, to promote resolution of inflammatory fibrotic disease.

STIFF-F

Segmental Tibial fractures, reamed Intramedullary nailing versus circular Frame external Fixation A feasibility study

WHITE-9

A multi centre randomised controlled trial comparing intra operative cell salvage with standard care in the treatment of hip fractures

FAME

The Fractured Ankle Management Evaluation

SPIN-OUT

• OCTRU
• SITU

The Spinal Fusion Indications and Outcomes Randomised Trial (SpInOuT)

ART

ART (Arterial Revascularisation Trial) is led by Professor David Taggart, Professor of Cardiovascular Surgery, University of Oxford.

HOPE-e

Hand Osteoarthritis: investigating Pain Effects in a randomised placebo-controlled feasibility study of estrogen-containing therapy (HOPE-e)

UK TAVI

The UK TAVI Trial is a multi-centre randomised controlled trial to assess the clinical effectiveness and cost-utility of TAVI, compared with conventional surgical aortic valve replacement.

SCIENCE

Surgery or Cast for Injuries of the EpicoNdyle in Children’s Elbows: A multi-centre prospective randomised superiority trial of operative fixation versus non-operative treatment for medial epicondyle fractures of the humerus.

6MP

This is a multi-centre randomised phase 2 trials in patients with known BRCA Defective Tumours

BKM120

This is a single centre Phase 1 trial of the PI3K inhibitor BKM120, given concomitantly with palliative radiotherapy for the treatment of Non-Small Cell Lung Cancer (NSCLC).