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The Aspirin Esomeprazole Chemoprevention Trial (AspECT) is to our knowledge one of the largest cancer prevention trials using aspirin and acid suppression in the world. In total 2557 patients with a common precancerous change in their oesophagus, called Barrett’s oesophagus, were followed up for an average of 9 years resulting in over 20,000 life-years of follow up. After informed written consent, patients were randomly allocated to four different combinations; Low acid suppression alone, High acid suppression alone, low acid suppression with 300mg aspirin and high acid suppression with 300mg aspirin. We wanted to see if we could prevent progression to local cancer/cancer in-situ (high grade dysplasia), invasive cancer or prevent death by all causes both cancer and non-cancer.
Trials Expertise Session: Patient and Public Involvement and Engagement (PPIE) in Trials
OCTRU
Wednesday, 13 November 2024, 10am to 11am
OCTRU Extended Training Bite: Introduction to OCTRU Database Systems
OCTRU
Thursday, 14 March 2024, 1pm to 3.30pm
OCTRU Training Bite: Creating your Data Matrix & REDCap Library *ONLINE*
OCTRU
Tuesday, 19 March 2024, 2pm to 3pm
OCTRU Training Bite: Research Ethics Committees (REC) - What they are, how they work and tips for an application *Online*
OCTRU
Wednesday, 17 April 2024, 1pm to 2pm
OCTRU Training Bite: Grant Development and Costing for Trial Managers - what needs to go in *Online*
OCTRU
Thursday, 23 May 2024, 2.30pm to 3.30pm
OCTRU Workshop How to identify required CRFs and develop fit for purpose CRFs (from protocol to CRFs)
OCTRU
Wednesday, 12 June 2024, 1.30pm to 4pm
OCTRU Extended Training Bite: Introduction to the Trial Master File *ONLINE*
OCTRU
Tuesday, 30 April 2024, 11am to 1pm
Trials Expertise Session: Communication skills in Clinical Trials for Trial Managers
OCTRU
Tuesday, 22 October 2024, 1pm to 2pm
Trials Expertise Session: Site Feasibility Questionnaire (SFQ) & Site selection *ONLINE*
OCTRU
Thursday, 16 May 2024, 10am to 11am
Trials Expertise Session: Site Initiation Visits (SIVs) *Hybrid*
OCTRU
Wednesday, 26 June 2024, 2.30pm to 3.30pm
OCTRU Extended Training Bite: Statistics for Non Statisticians
OCTRU
Tuesday, 26 November 2024, 9.30am to 12.30pm
OCTRU Training Bite: Research Ethics Committees (REC) - What they are, how they work and tips for an application *Online*
OCTRU
Tuesday, 08 October 2024, 10am to 11am
OCTRU Workshop: How to identify required CRFs and develop fit for purpose CRFs (from protocol to CRFs)
OCTRU
Thursday, 14 November 2024, 10am to 12.30pm
OCTRU Training Bite: Management of IMP and Relevant Documentation *ONLINE*
OCTRU
Tuesday, 03 December 2024, 1pm to 2.30pm
OCTRU Training Bite: An overview of the update to the SPIRIT and CONSORT guidelines
OCTRU
Thursday, 05 December 2024, 10am to 11.30am