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Escape Rooms
Karedla Group | Quantitative Immunodynamics Laboratory
A typical immune response involves a complex choreography of signalling molecules and cells operating in a physical world, where biological behaviour is governed by physical principles such as reaction-diffusion kinetics, nanoscale electrostatics, and statistical mechanics. Immune cells communicate across tightly confined contact zones where receptor spatiotemporal organization, the trafficking of signalling molecules, membrane fluctuations, and intermembrane interactions directly regulate their decisions. Our research aims to bridge the gap between biological observation and the underlying physics and chemistry by developing advanced, high-resolution light microscopy tools. By connecting these high-precision measurements to quantitative models, we aim to uncover the principles that shape immune function in complex biological systems, offering a new perspective that complements traditional genetics and opens new frontiers for drug development and therapeutic intervention.
SHADE-PsD - Sex Hormones and Disease Experience – Psoriatic Disease
Understanding patient experience of psoriatic disease with fluctuations in female sex hormones
PREPARE KIDS
Pre-Operative Rehabilitation (Prehabilitation) in Elective Lower Limb Paediatric Orthopaedic Surgery
Wiberg Group | Peripheral Nerve Research Lab
Translational research at the intersection of peripheral nerve surgery and laboratory science, working to develop better treatments for those living with nerve compression, nerve injury, and nerve pain.
Improving Wrist Injury Pathways (I-WIP)
Wrist injuries are a big and common problem for patients and the NHS, with around 70,000 patients a year in the UK going to hospitals with wrist pain after an injury and normal x-rays.
Dendrou Group | Immune Disease Multiomics
Our research aims to compare inflammatory diseases and immunological responses across tissues, over time and upon perturbation for translational benefit, leveraging multiomic technologies.
The CELLOS Study
Development of a core outcome set for children’s elective lower limb orthopaedic surgery