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Pioneering research by scientists at the Universities of Oxford and Birmingham published today in Nature brings us a step closer to developing targeted therapies for inflammatory diseases.

News Items (608)

NHS baby check may miss dislocated hips in new-born babies

25 April 2024

A new study has identified that NHS infant checks can miss serious hip abnormalities in new-born babies. Left undetected, these can require complex surgery, and lead to early arthritis. In the UK around 500 infants undergo surgery for dislocated hips which could have been avoidable.

New Study uses AI to predict malaria outbreaks in South Asia

23 April 2024

Researchers from NDORMS in collaboration with international institutions have demonstrated the potential of using environmental measurements and deep learning modeling to predict malaria outbreaks in South Asia. The study offers promising insights into improving early warning systems for one of the world's deadliest diseases.

HIPCARE trial launches in the Philippines

22 April 2024

Prof Matt Costa has just returned from the Philippines, where he launched the new HIPCARE trial with co-lead investigator Prof Irewin Tabu. The first of five Low- and Middle-Income Countries (LMIC) in Asia to take part, eight hospitals in the Philippines will start recruiting patients with fragility fractures of the hip to the study within weeks.

Justin Wormald wins NIHR awards and takes up position as SITU Deputy Director

17 April 2024

NDORMS alumnus Justin Wormald has been awarded an NIHR Academic Clinical Lectureship and an NIHR Development and Skills Enhancement (DSE) Award, as well as being appointed as Deputy Director of the Surgical Trials Intervention Unit (SITU-NDORMS).

New TRIPOD+AI guidelines reflect growing use of AI in healthcare research

16 April 2024

The widespread use of artificial intelligence (AI) in medical decision-making tools has led to an update of the TRIPOD guidelines for reporting clinical prediction models. The new TRIPOD+AI guidelines are launched in the BMJ today.

COVID-19 vaccines effectiveness: results from Norway demonstrate the reproducibility of federated analytics

11 April 2024

Researchers from NDORMS and the University of Oslo, have successfully replicated findings from recently published international studies on the effectiveness of COVID-19 vaccines to prevent long COVID and post-acute complications.

Connects-UK launches to foster scientific collaborations between EU and UK researchers in a post-Brexit era

10 April 2024

Connects-UK, a new pan-European network dedicated to advancing scientific collaborations between researchers in the European Union (EU) and the United Kingdom (UK), was officially launched at an event in London yesterday. The network, led by a diaspora of EU researchers working in the UK, seeks to bridge the gap created by Brexit and ensure that collaboration, innovative research, funding, and knowledge exchange continue to thrive in the post-Brexit era.

New study reveals how T cells gain and maintain tolerance to gut bacteria

4 April 2024

The immune system in the intestine maintains a careful balance, tolerating our long-term resident (commensal) gut bacteria while defending against invading pathogens. Under certain circumstances, dysregulation of our intestinal immune response to commensal and pathogenic microbes can drive inflammatory disease.

Simon Matthew Graham awarded an MRC Clinician Scientist Fellowship

26 March 2024

The award from the Medical Research Council (MRC) will support research to improve treatments for open fractures in low- and middle-income countries.

New framework guides the use of AI for clinical diagnosis

25 March 2024

NDORMS researchers have conducted a review of the literature on the use of AI in clinical decision-making. Published in the Lancet the study identifies why AI has not yet been taken up more widely, and provides a framework to better inform future adoption and integration of the technology.

New study reveals long-term mental health risks after COVID-19

21 March 2024

A new study published in Nature Human Behaviour sheds light on the long-term mental health consequences of COVID-19 infection and the growing evidence of the protective effect of vaccination on reducing the risk.

NDORMS’ Athena Swan Silver award renewed

20 March 2024

NDORMS has been awarded the Athena Swan Silver award for the third consecutive time, recognising the department’s commitment to gender equality.

AI Software yields six-fold increase in spine fracture identification

19 March 2024

Early findings in the ADOPT study, show that Nanox.AI software improves the detection of spine fractures, an early sign of osteoporosis, outperforming UK National Health Service national average.

Professor Gary Collins awarded prestigious NIHR Senior Investigator award

15 March 2024

NDORMS Professor of Medical Statistics and Director of the Centre for Statistics in Medicine, Gary Collins has been appointed National Institute of Health Research (NIHR) Senior Investigator.

New bronchoscopy capability expands capacity for respiratory and vaccine trials

14 March 2024

The NIHR Oxford Clinical Research Facility (EMCRF) hosted by NDORMS has expanded its capability to undertake research bronchoscopies. The facility welcomed its first volunteers as part of the Oxford Airways Study to help understand the causes of asthma.

COVID jab linked to lower risk of COVID-19-related clot and heart complications

13 March 2024

NDORMS research shows that vaccination reduced the risk of heart failure and some clot-related complications for up to a year.

PD-1 gets an “A” for team-work

8 March 2024

A new understanding of the PD-1 axis (programmed death cell) could help shape ongoing efforts to improve treatments for cancer and autoimmune diseases.

Professor Irina Udalova appointed to the MRC’s Infections and Immunity Board

1 March 2024

The Medical Research Council’s Infections and Immunity Board (IIB) funds research into infectious human disease and disorders of the human immune system.

Oxford-ZEISS Centre of Excellence officially opened

23 February 2024

ZEISS is partnering with the University of Oxford bringing ground-breaking microscopy imaging equipment, and analysis tools, to advance the study of global health and disease.

Removing bias from healthcare AI tools

22 February 2024

Rapid advances in Artificial Intelligence (AI) have opened the way for the creation of a huge range of new healthcare tools, but to ensure that these tools do not exacerbate preexisting health inequities, researchers urge the use of more representative data in their development.