New hope for patients with incurable and disabling Dupuytren’s disease

Nirmatrelvir-ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022-23: virological and immunological results of an open-label randomised trial (PANORAMIC).

Lowe DM. et al, (2027), Lancet Microbe

Multi-objective optimisation of 3D-printed multilayer TPMS osteochondral scaffolds for enhanced mechanical and biological performance

Xu Y. et al, (2026), Virtual and Physical Prototyping, 21

Subharmonics are not an infallible safety metric for cavitation dynamics.

Wu Q. et al, (2026), Int J Hyperthermia, 43

Assessing the Importance of Variation in Diagnostic Coding Among the Three Countries in the UK Biobank.

Clifton L. et al, (2026), Learn Health Syst, 10

Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL

Coates LC. et al, (2026), RMD Open, 20, e043855 - e043855

Optimal management of pyogenic flexor tenosynovitis of the hand: a cohort study

Hennessy M. et al, (2026), Journal of Hand and Microsurgery, 18

3D bone printing via ultrasound-mediated osteogenic differentiation of stem cells (3DBonUS).

Marcotulli M. et al, (2026), Biofabrication

National surveys on the use of local anaesthetic with adrenaline (LANTERN study) in the emergency setting.

Tam SSC. et al, (2026), Emerg Med J

Learned Geospatial Priors for Malaria Forecasting

Nazir U. et al, (2026)

Does social deprivation influence timely presentation of adolescent idiopathic scoliosis: a retrospective study.

Hussien A. et al, (2026), Spine Deform

Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases.

Koh B. et al, (2026), Nat Immunol

Incidence, Healthcare Resource Utilization, and Costs Associated with Intraoperative Ureteral Injuries: Evidence from a German Claims Database.

Muresan B. et al, (2026), Adv Ther

Radical Prostatectomy in Low-volume Metastatic Prostate Cancer? The Need for New Evidence.

Sooriakumaran P. et al, (2026), Eur Urol

Interferon-γ promotes SMAP production by cytotoxic T lymphocytes in a thrombospondin-4 dependent manner

Khamis OM. et al, (2026)

Burden and economic impact of RSV hospitalisations among English adults, 2023/24.

Truong T. et al, (2026), J Infect, 93

Beyond event-rate enrichment: proteomic risk scores for mechanism-aware prevention trial design

Fieggen J. et al, (2026)

PTPN22 regulates T cell synapse formation through PSTPIP1-dependent actin remodeling

Joseph MD. et al, (2026), Science Signaling, 19

First-line durvalumab in combination with trastuzumab deruxtecan in women with locally advanced unresectable or metastatic, hormone-receptor-negative, HER2-low breast cancer: multicenter, open-label, phase 1b/2 BEGONIA platform trial.

Schmid P. et al, (2026), Nat Cancer

The embryonic origins of site-specific arthritis.

Davidson S. et al, (2026), Nat Immunol

Assessing interannual variation in leaf chlorophyll dynamics using optical and destructive methods with mixed-effects and additive modelling

Khan R., (2026), Journal of Plant Research

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Nirmatrelvir-ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022-23: virological and immunological results of an open-label randomised trial (PANORAMIC).

Multi-objective optimisation of 3D-printed multilayer TPMS osteochondral scaffolds for enhanced mechanical and biological performance

Subharmonics are not an infallible safety metric for cavitation dynamics.

Assessing the Importance of Variation in Diagnostic Coding Among the Three Countries in the UK Biobank.

Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL

Optimal management of pyogenic flexor tenosynovitis of the hand: a cohort study

3D bone printing via ultrasound-mediated osteogenic differentiation of stem cells (3DBonUS).

National surveys on the use of local anaesthetic with adrenaline (LANTERN study) in the emergency setting.

Learned Geospatial Priors for Malaria Forecasting

Does social deprivation influence timely presentation of adolescent idiopathic scoliosis: a retrospective study.

Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases.

Incidence, Healthcare Resource Utilization, and Costs Associated with Intraoperative Ureteral Injuries: Evidence from a German Claims Database.

Radical Prostatectomy in Low-volume Metastatic Prostate Cancer? The Need for New Evidence.

Interferon-γ promotes SMAP production by cytotoxic T lymphocytes in a thrombospondin-4 dependent manner

Burden and economic impact of RSV hospitalisations among English adults, 2023/24.

Beyond event-rate enrichment: proteomic risk scores for mechanism-aware prevention trial design

PTPN22 regulates T cell synapse formation through PSTPIP1-dependent actin remodeling

First-line durvalumab in combination with trastuzumab deruxtecan in women with locally advanced unresectable or metastatic, hormone-receptor-negative, HER2-low breast cancer: multicenter, open-label, phase 1b/2 BEGONIA platform trial.

The embryonic origins of site-specific arthritis.

Assessing interannual variation in leaf chlorophyll dynamics using optical and destructive methods with mixed-effects and additive modelling

Meet the team

Jagdeep Nanchahal

Sir Marc Feldmann FRS

Fiona Powrie FRS

PROFESSOR Jagdeep Nanchahal talks about the Trial

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