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A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

Macrophage engulfing bacteria 3d illustration © Shutterstock
The new study shows the IL-10-PGE2 axis ensures macrophages are effective at killing potentially harmful bacteria

MANTIS

Managing Avascular Necrosis Treatments : An Interventional Study

WHITE-5

WHITE-5

FAIT

FAIT is a multicentre randomised controlled clinical trial comparing surgical and non-surgical approaches to treating femoroacetabular impingement (hip impingement).

WHITE-4

World Hip Trauma Evaluation Four

Glyn-Jones Group | Hip Research Group

Our research focuses on hip osteoarthritis, from identifying its causes to developing new surgery techniques for the condition.

MEET FIONA

  • Fiona Powrie FRS
    Fiona Powrie FRS

    Professor of Musculoskeletal Sciences and Director of the Kennedy Institute

FUNDED BY

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 Fondation Louis-Jeantet

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Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2
Journal of Experimental Medicine

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