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A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance
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Health Economics & Outcomes Research
Our research aims to improve people's health and wellbeing by making the most efficient use of health and social care resources. To achieve this, we use real-world data and mathematical models to evaluate the costs and consequences of applying different interventions over a period of time, often the entire lifetime of patients.
Dakin Group | Soft Tissue Joint Disease
The Dakin Group undertakes translational research focusing on identifying the cellular and molecular basis of inflammatory fibrotic soft tissue joint diseases, with research programmes on tendinopathy, frozen shoulder and knee arthrofibrosis. Understanding the cellular and molecular basis of these diseases will inform new therapeutic approaches targeting tissue resident stromal cells of the joint, to promote resolution of inflammatory fibrotic disease.
Hand Research Group
We are a collaborative group of academic researchers, therapists, physicians, and surgeons. We carry out a wide range of studies in patients, including observational studies of disease, basic science studies on patient-donated tissue and clinical trials of new treatments. Our ultimate aim is to improve the care of patients with hand and wrist problems.
MEET FIONA
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Fiona Powrie FRS
Professor of Musculoskeletal Sciences and Director of the Kennedy Institute
FUNDED BY
Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2
Journal of Experimental Medicine