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A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

Macrophage engulfing bacteria 3d illustration © Shutterstock
The new study shows the IL-10-PGE2 axis ensures macrophages are effective at killing potentially harmful bacteria

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MEET FIONA

  • Fiona Powrie FRS
    Fiona Powrie FRS

    Professor of Musculoskeletal Sciences and Director of the Kennedy Institute

FUNDED BY

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 Fondation Louis-Jeantet

National Institute for Health and Care Research logo

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2
Journal of Experimental Medicine

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