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New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.

Artists representation of T lymphoyctes. Signalling through TNFR2 receptor maintains Foxp3 expression in suppressor T lymphocytes.

Subharmonics are not an infallible safety metric for cavitation dynamics.

Wu Q. et al, (2026), Int J Hyperthermia, 43

Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL

Coates LC. et al, (2026), RMD Open, 20, e043855 - e043855

Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature.

Scherlinger M. et al, (2026), J Transl Autoimmun, 12

Recent advances in biomaterials and structural design of 3D printed multiphasic scaffolds for osteochondral regeneration

Xu Y. et al, (2026), Materials Science and Engineering: R: Reports, 170, 101210 - 101210

Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023)

Perletta V. et al, (2026), ESMO Real World Data and Digital Oncology, 12, 100700 - 100700

The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care.

Sharma A. et al, (2026), BJU Int, 137, 849 - 857

Deformation-Recovery diffusion model (DRDM): Instance deformation for image manipulation and synthesis.

Zheng J-Q. et al, (2026), Med Image Anal, 110

Identification of genetic risk loci associated with aquaporin 4-positive neuromyelitis optica spectrum disorder: a genome-wide association study.

Attfield KE. et al, (2026), Lancet Neurol, 25, 482 - 491

Reoperation in the year following a hip fracture : a nationwide cohort study in England.

Patel R. et al, (2026), Bone Joint J, 108-B, 698 - 706

Identifying the Initiation of a New Line of Therapy for Metastatic Lung, Breast, and Colorectal Cancer in Real-World Data: A Scoping Review.

Onasanya O. et al, (2026), Pharmacoepidemiol Drug Saf, 35

Age and symptom severity as predictors of outcomes following shockwave therapy in Achilles tendinopathy : a single-centre observational study.

Hutchison A-M. et al, (2026), Bone Joint J, 108-B, 650 - 656

Comparison of ultrasound contrast agent production by sonication and mechanical agitation

Stride E., (2026), Ultrasonics Sonochemistry

Healthcare Resource Use and Costs for Clusters of Patients with Multiple Long-Term Conditions: Findings from the UK Co-Action Study

Fabiano G. et al, (2026)

Metabolic profiling of steatotic liver disease by fluorescence lifetime imaging microscopy.

Purdie K. et al, (2026), Commun Med (Lond)

Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients.

Butler CC. et al, (2026), N Engl J Med, 394, 1583 - 1594

Hyaluronic Acid-Phosphatidylcholine Complexes as Reductionist Mimics of Extracellular Vesicle-Mediated Boundary Lubrication in Synovial Joints.

Zhu L. et al, (2026), Acta Biomater

Beyond expansion: workforce absence, administration and the persistence of NHS elective backlogs

Tealdi C. et al, (2026), Journal of the Royal Society of Medicine

Effect of Nipocalimab on IgG Responses to Vaccinations and Viral Infections in Patients with IgG Autoantibody–Mediated Diseases: Post Hoc Analyses of 3 Randomized, Placebo-Controlled Trials

Yu F. et al, (2026), Human Vaccines & Immunotherapeutics

Kv1.3 palmitoylation regulates spatial distribution and channel removal from the immunological synapse.

Navarro-Pérez M. et al, (2026), Cell Mol Life Sci

Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense.

Silvestre-Roig C. et al, (2026), Sci Immunol, 11

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Showing results for

Subharmonics are not an infallible safety metric for cavitation dynamics.

Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from the phase III BE COMPLETE study and its open-label extension BE VITAL

Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature.

Recent advances in biomaterials and structural design of 3D printed multiphasic scaffolds for osteochondral regeneration

Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023)

The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care.

Deformation-Recovery diffusion model (DRDM): Instance deformation for image manipulation and synthesis.

Identification of genetic risk loci associated with aquaporin 4-positive neuromyelitis optica spectrum disorder: a genome-wide association study.

Reoperation in the year following a hip fracture : a nationwide cohort study in England.

Identifying the Initiation of a New Line of Therapy for Metastatic Lung, Breast, and Colorectal Cancer in Real-World Data: A Scoping Review.

Age and symptom severity as predictors of outcomes following shockwave therapy in Achilles tendinopathy : a single-centre observational study.

Comparison of ultrasound contrast agent production by sonication and mechanical agitation

Healthcare Resource Use and Costs for Clusters of Patients with Multiple Long-Term Conditions: Findings from the UK Co-Action Study

Metabolic profiling of steatotic liver disease by fluorescence lifetime imaging microscopy.

Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients.

Hyaluronic Acid-Phosphatidylcholine Complexes as Reductionist Mimics of Extracellular Vesicle-Mediated Boundary Lubrication in Synovial Joints.

Beyond expansion: workforce absence, administration and the persistence of NHS elective backlogs

Effect of Nipocalimab on IgG Responses to Vaccinations and Viral Infections in Patients with IgG Autoantibody–Mediated Diseases: Post Hoc Analyses of 3 Randomized, Placebo-Controlled Trials

Kv1.3 palmitoylation regulates spatial distribution and channel removal from the immunological synapse.

Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense.

Meet the team

I-Shu Huang

Felix Clanchy

Sir Marc Feldmann FRS

Richard Williams

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