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The combination of hydroxychloroquine (HCQ) and azithromycin (AZM) has been linked to significant cardiovascular risks including mortality, in the largest safety study ever performed on both HCQ and HCQ+AZM.

Hydroxychloroquine spelt out in blocks
Hydroxychloroquine use with azithromycin has double relative risk of heart related death in short term

Subharmonics are not an infallible safety metric for cavitation dynamics.

Journal article

Wu Q. et al, (2026), Int J Hyperthermia, 43

Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature.

Journal article

Scherlinger M. et al, (2026), J Transl Autoimmun, 12

Comorbidities, medication use, and overall survival in eight cancers: a multinational cohort study of 1.7 million patients across Europe.

Journal article

López-Sánchez I. et al, (2026), Lancet Reg Health Eur, 63

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis.

Journal article

Beernaert B. et al, (2026), Sci Adv, 12

Validating Primary and Secondary Healthcare Resource Use and Costs estimates in OMOP-Mapped vs Source CPRD-HES Data in the UK

Conference paper

Pinedo Villanueva R., (2026)

Characteristics, treatment and survival of patients with chondrosarcoma in five European countries: a DARWIN EU® cohort study.

Journal article

Barchuk A. et al, (2026), Acta Oncol, 65, 193 - 200

Collectin-11 regulates osteoclastogenesis and bone maintenance via a complement-dependent mechanism

Journal article

Howard MC. et al, (2026), Proceedings of the National Academy of Sciences, 123

Unveiling the association between low-density lipoprotein cholesterol lowering and fracture risk : real-world evidence from a target trial emulation study.

Journal article

Wen Z. et al, (2026), Bone Joint Res, 15, 227 - 237

Implementation of OMOP and ConcePTION Common Data Models in CPRD GOLD: Risk of Bleeding and Cardiovascular Outcomes From Anticoagulant Use.

Journal article

Hunt NB. et al, (2026), Clin Pharmacol Ther

The adaptor protein TASL is required for age-related B cell emergence and lupus-like disease development in mice.

Journal article

Johnstone JC. et al, (2026), PLoS Biol, 24

Checkpoint blockade amplifies pro-regenerative type 2 immunity in tissue repair.

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Romero Arocha S. and Clarke A., (2026), Nat Rev Immunol

Lytic IFNγ is stored in cytotoxic granules and coreleased with granzyme B to mediate cytotoxic T lymphocyte killing.

Journal article

Li X. et al, (2026), Cell Mol Immunol

Surgery versus non-surgical splint treatment for proximal phalanx shaft finger fractures in adults: the POINT Randomised Controlled Trial.

Journal article

Karantana A. et al, (2026), Health Technol Assess, 1 - 41

Cohort Study on Drug Survival and Tolerability of Adalimumab Biosimilar Transitioning: Pharmaceutical Properties Do Matter.

Journal article

Peeters ACD. et al, (2026), Clin Pharmacol Ther, 119, 651 - 659

Determinants of six-minute walk test performance in individuals with knee osteoarthritis.

Journal article

Mylvaganam S. et al, (2026), Osteoarthr Cartil Open, 8

Supervised versus self-managed rehabilitation for patients with an acute first-time or recurrent patellar dislocation: the Physiotherapy Rehabilitation Post Patellar Dislocation (PRePPeD) external pilot randomized controlled trial and embedded qualitative study.

Journal article

Forde CP. et al, (2026), Bone Joint J, 108-B, 310 - 321

Time to reframe osteoporosis: a position statement to characterize the osteoporosis care gap.

Journal article

Paskins Z. et al, (2026), JBMR Plus, 10

Outcomes in Early Adulthood for Individuals Born Very Preterm and/or with Very Low Birth Weight: Evidence from Multinational Cohorts.

Journal article

Pilvar H. et al, (2026), J Pediatr Clin Pract, 19

Severe necrotizing soft tissue infections (SENSEI) study: Protocol for a multi-centered audit.

Journal article

Yoshimura R. et al, (2026), JPRAS Open, 48, 331 - 336

Quantitative Systems Pharmacology Models of Anti-Amyloid Treatments for Alzheimer's Disease: A Systematic Review.

Journal article

Herriott L. et al, (2026), CPT Pharmacometrics Syst Pharmacol, 15

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