Dani Prieto-Alhambra

MD MSc(Oxf) PhD

Professor of Pharmaco- and Device Epidemiology

Theme Lead for Observational Research, Centre for Statistics in Medicine
NIHR Senior Research Fellow
Fellow of the International Society of Pharmaco-Epidemiology, FISPE

Real World Evidence, Pharmaco-epidemiology, Device Epidemiology

I am an epidemiologist using routinely collected health data to generate reliable evidence for improved patient care here at the Centre for Statistics in Medicine in NDORMS.

Through an NIHR Senior Research Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions and amongst older people with complex health needs.

I lead Pharmaco- and Device Epidemiology research at NDORMS, and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on databases like the United Kingdom’s CPRD (formerly GPRD), Spain’s SIDIAP Database, Denmark’s Danish Health Registries, Italy’s HSD, and the Netherlands’ IPCI (Netherlands).

More recently, I have joined the European Health Data & Evidence Network EHDEN (www.ehden.eu) and the Observational Health Data Sciences and Informatics OHDSI (www.ohdsi.org) in an effort to accelerate and improve the quality of real world evidence internationally.

Key publications

GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.
Journal article

Roca-Ayats N. et al, (2017), N engl j med, 376, 1794 - 1795
Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.
Journal article

Kendal AR. et al, (2013), Bmj, 347
Primary hip replacement prostheses and their evidence base: systematic review of literature.
Journal article

Kynaston-Pearson F. et al, (2013), Bmj, 347
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet, 389, 1424 - 1430
Risk of hip, subtrochanteric, and femoral shaft fractures among mid and long term users of alendronate: nationwide cohort and nested case-control study.
Journal article

Abrahamsen B. et al, (2016), Bmj, 353

Recent publications

Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England.
Journal article

Ferguson R. et al, (2021), Bmj open, 11
Influence of pre-existing multimorbidity on receiving a hip arthroplasty: cohort study of 28 025 elderly subjects from UK primary care.
Journal article

Ferguson R. et al, (2021), Bmj open, 11
Correction to: Alendronate use and bone mineral density gains in women with moderate-severe (stages 3B-5) chronic kidney disease: an open cohort multivariable and propensity score analysis from Funen, Denmark.
Journal article

Ali MS. et al, (2021), Arch osteoporos, 16
Atopic-eczema-associated fracture risk and oral corticosteroids: a population-based cohort study
Journal article

Matthewman J. et al, (2021), The journal of allergy and clinical immunology
Knee and hip osteoarthritis and risk of nine cancers in a large real-world matched cohort study
Journal article

Turkiewicz A. et al, (2021), Rheumatology
“Association between COVID-19 vaccination, infection, and risk of Guillain-Barre syndrome, Bell’s palsy, encephalomyelitis and transverse myelitis: a population-based cohort and self-controlled case series analysis”
Journal article

Li X. et al, (2021)
Association of tramadol vs codeine prescription dispensation with mortality and other adverse clinical outcomes
Journal article

Xie J. et al, (2021), Jama
Timing of elective tracheotomy and duration of mechanical ventilation amongst patients admitted to intensive care with severe COVID-19: a multicentre prospective cohort study
Journal article

Prats Uribe A. and PRIETO ALHAMBRA D., (2021), Head and neck: journal for the sciences and specialities of the head and neck
Temporal Trends and Geographical Variation in Dupuytren Disease Surgery in England: A Population-Based Cohort Study.
Journal article

Alser O. et al, (2021), Ann plast surg, 87, 265 - 270
Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study.
Journal article

Cabezas C. et al, (2021), Bmj, 374

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