Dani Prieto-Alhambra

MD MSc(Oxf) PhD

Professor of Pharmaco- and Device Epidemiology

Section Head, Health Data Sciences, Botnar Research Centre
NIHR Senior Research Fellow
Fellow of the International Society of Pharmaco-Epidemiology, FISPE

Real World Evidence, Pharmaco-epidemiology, Device Epidemiology

I am an epidemiologist and academic clinician scientist using routinely collected (real world) health data to generate reliable evidence for improved patient care.

Through an NIHR Senior Research Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions and amongst older people with complex health needs.

I lead Pharmaco- and Device Epidemiology research at NDORMS, and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on multiple real world data assets nationally and internationally, and have specialized in network studies using the OMOP Common Data Model.

More recently, I have joined the European Health Data & Evidence Network EHDEN (www.ehden.eu) and the Observational Health Data Sciences and Informatics OHDSI (www.ohdsi.org) in an effort to accelerate and improve the quality of real world evidence internationally.

From February 2022, I am Deputy Director for the European Medicines Agency's Data Analysis and Real World Interrogation Network (DARWIN EU) Coordination Centre, and lead the Development pillar for the generation and/or validation of analytical tools to generate real world evidence for regulatory use.

Key publications

The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet, 389, 1424 - 1430
Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study.
Journal article

Cabezas C. et al, (2021), Bmj, 374
Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events: population based cohort and self-controlled case series analysis.
Journal article

Li X. et al, (2022), Bmj, 376
Characterising the background incidence rates of adverse events of special interest for COVID-19 vaccines across eight countries: a multinational network cohort study
Journal article

Li X. et al, (2021), The bmj
Comparative risk of thrombosis with thrombocytopenia syndrome or thromboembolic events associated with different covid-19 vaccines: international network cohort study from five European countries and the US.
Journal article

Li X. et al, (2022), Bmj, 379
Renin-angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis.
Journal article

Morales DR. et al, (2021), Lancet digit health, 3, e98 - e114
Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study.
Journal article

Lane JCE. et al, (2020), Lancet rheumatol, 2, e698 - e711
Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study.
Journal article

Burn E. et al, (2022), Lancet infect dis
Association of Tramadol vs Codeine Prescriptions With Mortality and Other Adverse Clinical Outcomes-Reply.
Journal article

Xie J. et al, (2022), Jama, 327, 489 - 490
Clinical and Genetic Risk Factors for Acute Incident Venous Thromboembolism in Ambulatory Patients With COVID-19.
Journal article

Xie J. et al, (2022), Jama intern med

Recent publications

Global epidemiology of hip fractures: secular trends in incidence rate, post-fracture treatment, and all-cause mortality.
Journal article

Sing C-W. et al, (2023), J bone miner res
The burden of long COVID: a multinational cohort analysis of Spanish and UK data including SARS-CoV-2 infections, reinfections, and matched contemporaneous test negative controls
Journal article

Kostka K. et al, (2023), Research square
Contextualising adverse events of special interest to characterise the baseline incidence rates in 24 million patients with COVID-19 across 26 databases: a multinational retrospective cohort study
Journal article

Voss EA. et al, (2023), Eclinicalmedicine, 58
The burden of long COVID: a multinational cohort analysis of Spanish and UK data including SARS-CoV-2 infections, reinfections, and matched contemporaneous test negative controls
Preprint

Prieto-Alhambra D. et al, (2023)
Safety outcomes of selective serotonin reuptake inhibitors in adolescent attention-deficit/hyperactivity disorder with comorbid depression: the ASSURE study.
Journal article

Kim C. et al, (2023), Psychol med, 1 - 9
Characterising complex health needs and the use of preventive therapies in the older population: a population-based cohort analysis of UK primary care and hospital linked data
Journal article

ELHUSSEIN L. et al, (2023), Bmc geriatrics
Risk of COVID-19 Diagnosis and Hospitalisation in Patients with Osteoarthritis or Back Pain Treated with Ibuprofen Compared to Other NSAIDs or Paracetamol: A Network Cohort Study.
Journal article

Xie J. et al, (2023), Drugs, 1 - 15
Classification of patients with osteoarthritis through clusters of comorbidities using 633,330 individuals from Spain
Journal article

Pineda Moncusi M. et al, (2023), Rheumatology
Contribution of genetics and lifestyle to the risk of major cardiovascular and thromboembolic complications following COVID-19
Preprint

Prieto-Alhambra D. et al, (2023)
Characterising the treatment of thromboembolic events after COVID-19 vaccination in 4 European countries and the US: An international network cohort study.
Journal article

Markus AF. et al, (2023), Front pharmacol, 14

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Dani Prieto-Alhambra

Key publications

Recent publications