Dani Prieto-Alhambra

MD MSc(Oxf) PhD

Professor of Pharmaco- and Device Epidemiology

Theme Lead for Observational Research, Centre for Statistics in Medicine
NIHR Clinician Scientist

I am an epidemiologist using routinely collected big health data to understand the epidemiology of musculoskeletal conditions here at the Centre for Statistics in Medicine in NDORMS.

Through an NIHR Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions.

I lead database and pharmaco-epidemiological research within the Epidemiology research group in NDORMS and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on databases like the United Kingdom’s CPRD (formerly GPRD), Spain’s SIDIAP Database, Denmark’s Danish Health Registries, Italy’s HSD, and the Netherlands’ IPCI (Netherlands).

BIOGRAPHY

I studied Medical Sciences at the Autonomous University of Barcelona in Spain (1996-2002), qualified as a General Practitioner in 2006, and obtained an MSc in Primary Care Research from the Autonomous University of Barcelona in 2009. I joined NDORMS in June 2009 to work on the epidemiology of musculoskeletal conditions. I was awarded an “excellent cum laude, with a European mention” PhD in 2011 for my work on the potential role of bisphosphonates in knee osteoarthritis and fractures.

I have since also obtained an MSc in Musculoskeletal Sciences from NDORMS (University of Oxford) and a Certificate in Pharmaco-epidemiology and Pharmacovigilance from the London School of Hygiene and Tropical Medicine.

Key publications

Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.
Journal article

Kendal AR. et al, (2013), Bmj (clinical research ed.), 347
Risk of hip, subtrochanteric, and femoral shaft fractures among mid and long term users of alendronate: nationwide cohort and nested case-control study.
Journal article

Abrahamsen B. et al, (2016), The bmj, 353
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet (london, england), 389, 1424 - 1430
GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.
Journal article

Roca-Ayats N. et al, (2017), The new england journal of medicine, 376, 1794 - 1795
Primary hip replacement prostheses and their evidence base: systematic review of literature.
Journal article

Kynaston-Pearson F. et al, (2013), The bmj, 347

Recent publications

Maintenance low dose systemic glucocorticoids have limited impact on bone strength and mineral density among incident renal allograft recipients: A pilot prospective cohort study.
Journal article

Pérez-Sáez MJ. et al, (2018), Bone, 116, 290 - 294
Development and validation of prediction models to estimate risk of primary total hip and knee replacements using data from the UK: two prospective open cohorts using the UK Clinical Practice Research Datalink.
Journal article

Yu D. et al, (2018), Ann rheum dis
Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on “real-world” data: a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database
Journal article

Khalid S. et al, (2018), Clinical epidemiology, Volume 10, 1417 - 1431
Non-Alcoholic Fatty Liver Disease and Risk of Acute Myocardial Infarction and Stroke: Analysis of 18 Million Patients in Four European Primary Care Databases.
Conference paper

Alexander M. et al, (2018), Hepatology, 68, 1323A - 1323A
Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease
Journal article

Alexander M. et al, (2018), Bmc medicine, 16
Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease.
Journal article

Alexander M. et al, (2018), Bmc medicine, 16
Oral bisphosphonate use and all-cause mortality in patients with advanced (stage IIIB plus ) chronic kidney disease: A propensity score analysis
Conference paper

Alarkawi D. et al, (2018), Pharmacoepidemiology and drug safety, 27, 185 - 186
Risk of osteoporotic fractures in new users of denosumab compared with new users of alendronate: A Danish population-based cohort study
Conference paper

Pedersen AB. et al, (2018), Pharmacoepidemiology and drug safety, 27, 406 - 407
Increasing risk of post-surgery infections among hip fracture patients: A nationwide study 2005-2016
Conference paper

Kjoerholt KE. et al, (2018), Pharmacoepidemiology and drug safety, 27, 482 - 483
Primary care recorded NAFLD and the risk of incident MI and stroke: Findings from analyses of 18 million patients in the UK, the Netherlands, Spain, and Italy
Conference paper

Alexander M. et al, (2018), Pharmacoepidemiology and drug safety, 27, 81 - 82

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