Dani Prieto-Alhambra

MD MSc(Oxf) PhD

Professor of Pharmaco- and Device Epidemiology

Theme Lead for Observational Research, Centre for Statistics in Medicine
NIHR Clinician Scientist

I am an epidemiologist using routinely collected big health data to understand the epidemiology of musculoskeletal conditions here at the Centre for Statistics in Medicine in NDORMS.

Through an NIHR Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions.

I lead database and pharmaco-epidemiological research within the Epidemiology research group in NDORMS and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on databases like the United Kingdom’s CPRD (formerly GPRD), Spain’s SIDIAP Database, Denmark’s Danish Health Registries, Italy’s HSD, and the Netherlands’ IPCI (Netherlands).

BIOGRAPHY

I studied Medical Sciences at the Autonomous University of Barcelona in Spain (1996-2002), qualified as a General Practitioner in 2006, and obtained an MSc in Primary Care Research from the Autonomous University of Barcelona in 2009. I joined NDORMS in June 2009 to work on the epidemiology of musculoskeletal conditions. I was awarded an “excellent cum laude, with a European mention” PhD in 2011 for my work on the potential role of bisphosphonates in knee osteoarthritis and fractures.

I have since also obtained an MSc in Musculoskeletal Sciences from NDORMS (University of Oxford) and a Certificate in Pharmaco-epidemiology and Pharmacovigilance from the London School of Hygiene and Tropical Medicine.

Key publications

Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.
Journal article

Kendal AR. et al, (2013), Bmj, 347
Risk of hip, subtrochanteric, and femoral shaft fractures among mid and long term users of alendronate: nationwide cohort and nested case-control study.
Journal article

Abrahamsen B. et al, (2016), Bmj, 353
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet, 389, 1424 - 1430
GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.
Journal article

Roca-Ayats N. et al, (2017), N engl j med, 376, 1794 - 1795
Primary hip replacement prostheses and their evidence base: systematic review of literature.
Journal article

Kynaston-Pearson F. et al, (2013), Bmj, 347

Recent publications

Recorded diagnosis of NAFLD and the risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults
Journal article

Alexander M. et al, (2019), Bmj
The association between type 2 diabetes mellitus, hip fracture, and post hip fracture mortality: a multi-state cohort analysis
Journal article

Tebé C. et al, (2019), Osteoporosis international
Unplanned admissions for patients with myeloma in the UK: Low frequency but high costs.
Journal article

Kolovos S. et al, (2019), J bone oncol, 17
Development and validation of patient-level prediction models for adverse outcomes following total knee arthroplasty in osteoarthritic patients
Conference paper

Williams R. et al, (2019)
Negative control outcomes to control for unmeasured confounding in device safety research: a clinical example
Conference paper

PRIETO ALHAMBRA D. et al, (2019)
Tramadol analgesic use as a screening tool for Total Hip Arthroplasty implant survival: A Population-based cohort study
Conference paper

MALAK TT. et al, (2019)
Bariatric surgery increases the risk of major osteoporotic fracture: a self-controlled case series patients from the CPRD GOLD database linked to HES
Conference paper

ROBINSON D. et al, (2019)
Propensity score stratification and inverse probability weighting compared to surgical randomised clinical trial results in device epidemiology
Conference paper

STRAUSS V. et al, (2019)
Self controlled case series in surgical epidemiology: checking the underlying assumptions in an empirical example
Conference paper

ROBINSON D. et al, (2019)
The performance of preference-based instrumental variables to emulate a randomised clinical trial of comparative medical device effectiveness
Conference paper

Prats-Uribe A. et al, (2019)

More publications