Dani Prieto-Alhambra

MD MSc(Oxf) PhD

Professor of Pharmaco- and Device Epidemiology

Theme Lead for Observational Research, Centre for Statistics in Medicine
NIHR Senior Research Fellow
Fellow of the International Society of Pharmaco-Epidemiology, FISPE

Real World Evidence, Pharmaco-epidemiology, Device Epidemiology

I am an epidemiologist using routinely collected health data to generate reliable evidence for improved patient care here at the Centre for Statistics in Medicine in NDORMS.

Through an NIHR Senior Research Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions and amongst older people with complex health needs.

I lead Pharmaco- and Device Epidemiology research at NDORMS, and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on databases like the United Kingdom’s CPRD (formerly GPRD), Spain’s SIDIAP Database, Denmark’s Danish Health Registries, Italy’s HSD, and the Netherlands’ IPCI (Netherlands).

More recently, I have joined the European Health Data & Evidence Network EHDEN (www.ehden.eu) and the Observational Health Data Sciences and Informatics OHDSI (www.ohdsi.org) in an effort to accelerate and improve the quality of real world evidence internationally.

Key publications

GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.
Journal article

Roca-Ayats N. et al, (2017), N engl j med, 376, 1794 - 1795
Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.
Journal article

Kendal AR. et al, (2013), Bmj, 347
Primary hip replacement prostheses and their evidence base: systematic review of literature.
Journal article

Kynaston-Pearson F. et al, (2013), Bmj, 347
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet, 389, 1424 - 1430
Risk of hip, subtrochanteric, and femoral shaft fractures among mid and long term users of alendronate: nationwide cohort and nested case-control study.
Journal article

Abrahamsen B. et al, (2016), Bmj, 353

Recent publications

Baseline characteristics, management, and outcomes of 55,270 children and adolescents diagnosed with COVID-19 and 1,952,693 with influenza in France, Germany, Spain, South Korea and the United States: an international network cohort study.
Working paper

Duarte-Salles T. et al, (2020), Medrxiv
Baseline phenotype and 30-day outcomes of people tested for COVID-19: an international network cohort including >3.32 million people tested with real-time PCR and >219,000 tested positive for SARS-CoV-2 in South Korea, Spain and the United States.
Working paper

Golozar A. et al, (2020), Medrxiv
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
Journal article

Burn E. et al, (2020), Nat commun, 11
Serious complications and risk of re-operation after Dupuytren's disease surgery: a population-based cohort study of 121,488 patients in England.
Journal article

Alser O. et al, (2020), Sci rep, 10
Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs.
Journal article

Fuggle NR. et al, (2020), Drugs, 80, 1537 - 1552
Childhood overweight and obesity and back pain risk: a cohort study of 466 997 children.
Journal article

Palmer AJ. et al, (2020), Bmj open, 10
Costs of joint replacement in osteoarthritis: a study using the National Joint Registry and Clinical Practice Research Datalink datasets
Journal article

LEAL J. et al, (2020), Arthritis care and research
Facing Tracheotomy in Critically ill Patients with COVID-19: a cohort analysis of timing, complications, and surgical team infection/s.
Journal article

Avilés-Jurado FX. et al, (2020), Jama otolaryngology-head and neck surgery
Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study.
Journal article

Lane JCE. et al, (2020), Lancet rheumatol
Filling the gaps in the characterisation of the clinical management of COVID-19: thirty-day hospital admission and fatality rates in a cohort of 118,150 cases diagnosed in outpatient settings in Spain
Journal article

PRIETO ALHAMBRA D. et al, (2020), International journal of epidemiology

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