Daniel Prieto-Alhambra

MD MSc(Oxf) PhD

Associate Professor and NIHR Clinician Scientist

Theme Lead for Observational Research, Centre for Statistics in Medicine

I am an epidemiologist using routinely collected big health data to understand the epidemiology of musculoskeletal conditions here at the Centre for Statistics in Medicine in NDORMS.

Through an NIHR Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions.

I lead database and pharmaco-epidemiological research within the Epidemiology research group in NDORMS and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on databases like the United Kingdom’s CPRD (formerly GPRD), Spain’s SIDIAP Database, Denmark’s Danish Health Registries, Italy’s HSD, and the Netherlands’ IPCI (Netherlands).

BIOGRAPHY

I studied Medical Sciences at the Autonomous University of Barcelona in Spain (1996-2002), qualified as a General Practitioner in 2006, and obtained an MSc in Primary Care Research from the Autonomous University of Barcelona in 2009. I joined NDORMS in June 2009 to work on the epidemiology of musculoskeletal conditions. I was awarded an “excellent cum laude, with a European mention” PhD in 2011 for my work on the potential role of bisphosphonates in knee osteoarthritis and fractures.

I have since also obtained an MSc in Musculoskeletal Sciences from NDORMS (University of Oxford) and a Certificate in Pharmaco-epidemiology and Pharmacovigilance from the London School of Hygiene and Tropical Medicine.

Key publications

Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.
Journal article

Kendal AR. et al, (2013), BMJ (Clinical research ed.), 347
Risk of hip, subtrochanteric, and femoral shaft fractures among mid and long term users of alendronate: nationwide cohort and nested case-control study.
Journal article

Abrahamsen B. et al, (2016), BMJ (Clinical research ed.), 353
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet (London, England), 389, 1424 - 1430
GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.
Journal article

Roca-Ayats N. et al, (2017), The New England journal of medicine, 376, 1794 - 1795
Primary hip replacement prostheses and their evidence base: systematic review of literature.
Journal article

Kynaston-Pearson F. et al, (2013), BMJ (Clinical research ed.), 347

Recent publications

Association between NICE guidance on biologic therapies with rates of hip and knee replacement among rheumatoid arthritis patients in England and Wales: An interrupted time-series analysis.
Journal article

Hawley S. et al, (2018), Seminars in arthritis and rheumatism, 47, 605 - 610
Mapping existing hip and knee replacement registries in Europe
Journal article

Lübbeke A. et al, (2018), Health Policy
Rheumatoid factor testing in Spanish primary care: A population-based cohort study including 4.8 million subjects and almost half a million measurements.
Journal article

Morsley K. et al, (2018), Reumatologia clinica
Spanish National Hip Fracture Registry (SNHFR): a description of its objectives, methodology and implementation.
Journal article

Sáez-López P. et al, (2018), Revista espanola de geriatria y gerontologia
Analgesic Use and Risk for Acute Coronary Events in Patients With Osteoarthritis: A Population-based, Nested Case-control Study.
Journal article

Pontes C. et al, (2018), Clinical therapeutics, 40, 270 - 283
Trends and determinants of length of stay and hospital reimbursement following knee and hip replacement: evidence from linked primary care and NHS hospital records from 1997 to 2014.
Journal article

Burn E. et al, (2018), BMJ open, 8
Oral bisphosphonate use and age-related macular degeneration: retrospective cohort and nested case-control study.
Journal article

Garriga C. et al, (2018), Annals of the New York Academy of Sciences
ACL and meniscal injuries increase the risk of primary total knee replacement for osteoarthritis: a matched case-control study using the Clinical Practice Research Datalink (CPRD).
Journal article

Khan T. et al, (2018), British journal of sports medicine
Association between chronic immune-mediated inflammatory diseases and cardiovascular risk.
Journal article

Baena-Díez JM. et al, (2018), Heart (British Cardiac Society), 104, 119 - 126
Prevalence of vertebral fracture and densitometric osteoporosis in Spanish adult men: The Camargo Cohort Study.
Journal article

Olmos JM. et al, (2018), Journal of bone and mineral metabolism, 36, 103 - 110

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