Dani Prieto-Alhambra

MD MSc(Oxf) PhD

Professor of Pharmaco- and Device Epidemiology

Theme Lead for Observational Research, Centre for Statistics in Medicine
NIHR Senior Research Fellow
Fellow of the International Society of Pharmaco-Epidemiology, FISPE

Real World Evidence, Pharmaco-epidemiology, Device Epidemiology

I am an epidemiologist using routinely collected health data to generate reliable evidence for improved patient care here at the Centre for Statistics in Medicine in NDORMS.

Through an NIHR Senior Research Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions and amongst older people with complex health needs.

I lead Pharmaco- and Device Epidemiology research at NDORMS, and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on databases like the United Kingdom’s CPRD (formerly GPRD), Spain’s SIDIAP Database, Denmark’s Danish Health Registries, Italy’s HSD, and the Netherlands’ IPCI (Netherlands).

More recently, I have joined the European Health Data & Evidence Network EHDEN (www.ehden.eu) and the Observational Health Data Sciences and Informatics OHDSI (www.ohdsi.org) in an effort to accelerate and improve the quality of real world evidence internationally.

Key publications

GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.
Journal article

Roca-Ayats N. et al, (2017), N engl j med, 376, 1794 - 1795
Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.
Journal article

Kendal AR. et al, (2013), Bmj, 347
Primary hip replacement prostheses and their evidence base: systematic review of literature.
Journal article

Kynaston-Pearson F. et al, (2013), Bmj, 347
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet, 389, 1424 - 1430
Risk of hip, subtrochanteric, and femoral shaft fractures among mid and long term users of alendronate: nationwide cohort and nested case-control study.
Journal article

Abrahamsen B. et al, (2016), Bmj, 353

Recent publications

Descriptive epidemiology of hip and knee replacement in rheumatoid arthritis: An analysis of UK electronic medical records.
Journal article

Hawley S. et al, (2020), Semin arthritis rheum, 50, 237 - 244
Is there a need for review-a-thons? – Authors' reply
Journal article

Prieto-Alhambra D. et al, (2020), The lancet rheumatology, 2, e205 - e207
SECULAR TRENDS IN THE INITIATION OF THERAPY IN SECONDARY FRACTURE PREVENTION IN EUROPE: A MULTI-NATIONAL COHORT STUDY INCLUDING DATA FROM DENMARK, CATALONIA, AND THE UNITED KINGDOM
Journal article

Skjødt MK. et al, (2020), Osteoporosis international
Dupuytren's Disease Predicts Increased All-Cause and Cancer-Specific Mortality: Analysis of a Large Cohort from the U.K. Clinical Practice Research Datalink.
Journal article

Kuo RYL. et al, (2020), Plast reconstr surg, 145, 574e - 582e
Incidence, risk factors and re-exacerbation rate of severe asthma exacerbations in a multinational, multidatabase pediatric cohort study.
Journal article

Engelkes M. et al, (2020), Pediatr allergy immunol
Prevalence and Mortality of Individuals With X-Linked Hypophosphatemia: A United Kingdom Real-World Data Analysis.
Journal article

Hawley S. et al, (2020), J clin endocrinol metab, 105
Multinational cohort study of mortality in patients with asthma and severe asthma
Journal article

Engelkes M. et al, (2020), Respiratory medicine
CHARACTERIZATION OF COMORBIDITY IN X-LINKED HYPOPHOSPHATAEMIA: A PROSPECTIVE PARALLEL COHORT STUDY USING THE UK CPRD
Conference paper

HAWLEY S. et al, (2020)
IMMINENT FRACTURE INCIDENCE AMONG INDEX FRACTURE PATIENTS WITH MULTIPLE MYELOMA RELATIVE TO GENERAL POPULATION CONTROLS: A PARALLEL COHORT STUDY OF THE UK CPRD
Conference paper

HAWLEY S. et al, (2020)
OVERALL FRACTURE INCIDENCE IN MULTIPLE MYELOMA PATIENTS RELATIVE TO GENERAL POPULATION CONTROLS: A PARALLEL COHORT STUDY OF THE UK CPRD
Conference paper

HAWLEY S. et al, (2020)

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