Dani Prieto-Alhambra

MD MSc(Oxf) PhD

Professor of Pharmaco- and Device Epidemiology

Theme Lead for Observational Research, Centre for Statistics in Medicine
NIHR Senior Research Fellow
Fellow of the International Society of Pharmaco-Epidemiology, FISPE

Real World Evidence, Pharmaco-epidemiology, Device Epidemiology

I am an epidemiologist using routinely collected health data to generate reliable evidence for improved patient care here at the Centre for Statistics in Medicine in NDORMS.

Through an NIHR Senior Research Fellowship, I am investigating the use, safety, effectiveness and cost of drugs and devices as used in usual practice conditions and amongst older people with complex health needs.

I lead Pharmaco- and Device Epidemiology research at NDORMS, and have experience designing, analysing and interpreting electronic medical records from around the world. I’ve worked on databases like the United Kingdom’s CPRD (formerly GPRD), Spain’s SIDIAP Database, Denmark’s Danish Health Registries, Italy’s HSD, and the Netherlands’ IPCI (Netherlands).

More recently, I have joined the European Health Data & Evidence Network EHDEN (www.ehden.eu) and the Observational Health Data Sciences and Informatics OHDSI (www.ohdsi.org) in an effort to accelerate and improve the quality of real world evidence internationally.

Key publications

GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.
Journal article

Roca-Ayats N. et al, (2017), N engl j med, 376, 1794 - 1795
Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.
Journal article

Kendal AR. et al, (2013), Bmj, 347
Primary hip replacement prostheses and their evidence base: systematic review of literature.
Journal article

Kynaston-Pearson F. et al, (2013), Bmj, 347
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.
Journal article

Bayliss LE. et al, (2017), Lancet, 389, 1424 - 1430
Risk of hip, subtrochanteric, and femoral shaft fractures among mid and long term users of alendronate: nationwide cohort and nested case-control study.
Journal article

Abrahamsen B. et al, (2016), Bmj, 353

Recent publications

Safety of oral bisphosphonates in moderate-to-severe chronic kidney disease: a bi-national cohort analysis.
Journal article

Robinson DE. et al, (2020), J bone miner res
The natural history of symptomatic COVID-19: a multi-state model of the first wave in Catalonia, including 102,002 outpatient diagnoses, 16,901 hospitalisations, and 5,273 COVID-19 deaths among 5,586,521 people
Journal article

Burn E. et al, (2020), Nature communications
Higher prevalence of non-skeletal comorbidity related to X-linked hypophosphataemia: a UK parallel cohort study using CPRD.
Journal article

Hawley S. et al, (2020), Rheumatology (oxford)
High Blood Pressure and Risk of Dementia: a Two-Sample Mendelian Randomization study in the UK Biobank
Journal article

SPROVIERO W. et al, (2020), Biological psychiatry
Body mass index and risk of COVID-19 diagnosis, hospitalisation, and death: a population-based multi-state cohort analysis including 2,524,926 people in Catalonia, Spain
Journal article

Recalde M. et al, (2020)
Characteristics, outcomes, and mortality amongst 133,589 patients with prevalent autoimmune diseases diagnosed with, and 48,418 hospitalised for COVID-19: a multinational distributed network cohort analysis.
Working paper

Tan EH. et al, (2020), Medrxiv
Evaluation of the COVID-19 response in Spain: principles and requirements.
Journal article

García-Basteiro AL. et al, (2020), Lancet public health, 5
Baseline characteristics, management, and outcomes of 55,270 children and adolescents diagnosed with COVID-19 and 1,952,693 with influenza in France, Germany, Spain, South Korea and the United States: an international network cohort study.
Working paper

Duarte-Salles T. et al, (2020), Medrxiv
Baseline phenotype and 30-day outcomes of people tested for COVID-19: an international network cohort including >3.32 million people tested with real-time PCR and >219,000 tested positive for SARS-CoV-2 in South Korea, Spain and the United States.
Working paper

Golozar A. et al, (2020), Medrxiv
“Clinical characteristics, symptoms, management and health outcomes in 8,598 pregnant women diagnosed with COVID-19 compared to 27,510 with seasonal influenza in France, Spain and the US: a network cohort analysis”
Working paper

Lai LYH. et al, (2020)

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