Contact information
Colleges
Jennifer Lane
MA MEd DPhil FRCS(Tr&Orth)
Honorary Clinical Research Fellow, Trauma and Orthopaedic Surgery
- MRC Doctoral Training Fellow (2017-2021)
- Versus Arthritis Research Fellow (2017-2021)
- NIHR Academic Clinical Fellow (2014-17)
- NIHR Academic Clinical Lecturer (2022-) Queen Mary, University of London
Using Big Data to improve the role of surgery in medical care
Jenny studied undergraduate medicine at Exeter College, Oxford, where she was awarded Scholar status. Graduating from clinical medicine in 2010, she undertook basic medical and surgical training in London. In 2014, Jenny graduated with distinction from Masters of Surgical Education degree at Imperial College, London, and returned to Oxford as NIHR Academic Clinical Fellow and Specialist Registrar in Orthopaedic Surgery. She was awarded a Versus Arthritis Clinical Research Fellowship and a MRC Doctoral Training Fellowship in July 2017, and began her DPhil in the Epidemiology of Common Hand Conditions in December 2017.
Main research interests
International real world data in surgical and device epidemiology (OHDSI)
In the post doctoral space Jenny is building upon her DPhil research in international federated network analyses to generate large scale collaborative epidemiological studies. Working within the OHDSI data science community, her research aims to use real world data to improve our understanding of surgical treatments and populations, in addition to the role of surgical devices in routine clinical practice. Her initial interest in hand surgery led her to lead the British Society for Surgery of the Hand (BSSH) first studyathon in September 2021, where a group of 30 surgeons and data scientists aimed to characterise patients presenting with wrist arthritis. Her future work aims to continue to work with global partners to focus on other areas of trauma and orthopaedic surgical disease where evidence in routine clinical practice is lacking, or rare diseases lend themselves to observational research methods.
Epidemiology of common hand conditions
During her DPhil, Jenny worked with Professor Dominic Furniss and Professor Dani Prieto Alhambra within NDORMS alongside Professor Jane Green in the Nuffield Department of Population Health. She is interested in how big data can be recycled to improve our understanding of hand disease and the role of surgery within treatment.
Her Versus Arthritis and MRC sponsored project aimed to improve our understanding of the the surgical management of common hand conditions using routinely collected UK GP and hospital data. Initially the work focussed upon investigating trends in surgery, and factors associated with adverse outcomes, before moving to compare UK data with other countries, in order to explore differences in surgeon, hospital and healthcare factors that may impact outcomes from surgery.
Impact of hormones on musculoskeletal conditions
As part of her DPhil study Jenny is also investigated the role of hormonal factors upon the development and progression of carpal tunnel syndrome and base of thumb osteoarthritis. Using the Million Women Study, she explored reproductive and menopausal factors that may be implicated in developing surgical disease. She is also investigated the interaction of hormonal treatments with musculoskeletal disease to better characterise the role of hormonal factors.
Surgical Education
Jenny has undertaken qualitative research investigating the impact of the introduction of the major trauma network upon higher orthopaedic training, and the results debated at a national level. Passionate about improving surgical training, she co-led a redesign of the University’s undergraduate orthopaedic trauma surgery programme with Mr Steve Gwilym, incorporating new elements of simulation technology to enrich the course. She has previously been an educational supervisor for the medical school, and was a surgical tutor at Exeter College, Oxford. She currently lectures in 'Big Data' for the Masters course in Surgical Science & Practice, University of Oxford in addition to the NDORMS Introductory DPhil lecture series.
Key publications
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Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study
Preprint
LANE J. et al, (2020)
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Preschool Obesity Is Associated With an Increased Risk of Childhood Fracture: A Longitudinal Cohort Study of 466,997 Children and Up to 11 Years of Follow-up in Catalonia, Spain.
Journal article
Lane JC. et al, (2020), J bone miner res, 35, 1022 - 1030
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Serious adverse events and lifetime risk of reoperation after elective shoulder replacement: population based cohort study using hospital episode statistics for England.
Journal article
Craig RS. et al, (2019), Bmj, 364
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Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study.
Journal article
Lane JCE. et al, (2020), Lancet rheumatol, 2, e698 - e711
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Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
Journal article
Burn E. et al, (2020), Nat commun, 11
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Basal thumb osteoarthritis surgery improves health state utility irrespective of technique: a study of UK Hand Registry data.
Journal article
Lane JCE. et al, (2020), J hand surg eur vol, 45, 436 - 442
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Low rate of subsequent surgery and serious complications following intra-articular steroid injection for base of thumb osteoarthritis: national cohort analysis.
Journal article
Lane JCE. et al, (2021), Rheumatology (oxford), 60, 4262 - 4271
Recent publications
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Epidemiology of acute flexor tendon injury and an analysis of outcomes - a study of 91,239 patients in England and Wales.
Journal article
Mawhinney JA. et al, (2025), J hand surg eur vol
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The burden of hand trauma surgery on primary care in the United Kingdom: a nation-wide analysis of antibiotic and opioid prescriptions.
Journal article
Wormald JC. et al, (2025), J hand surg eur vol
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Epidemiology of upper limb necrotising fasciitis in England: A national study (1998-2018).
Journal article
Ang K-L. et al, (2025), J plast reconstr aesthet surg, 104, 334 - 338
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Changes in hand function and health state utility after cubital tunnel release using the United Kingdom Hand Registry.
Journal article
Teunissen JS. et al, (2025), J hand surg eur vol, 50, 344 - 351
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Facilitating clinical trials in hip fracture in the UK : the role and potential of the National Hip Fracture Database and routinely collected data.
Journal article
Webster J. et al, (2025), Bone joint j, 107-B, 229 - 238
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The association of bariatric surgery and carpal tunnel syndrome: A propensity score-matched cohort study.
Journal article
Lane J. et al, (2024), J plast reconstr aesthet surg, 97, 245 - 255
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Time Series Methods to Assess the Impact of Regulatory Action: A Study of UK Primary Care and Hospital Data on the Use of Fluoroquinolones.
Journal article
Guo Y. et al, (2024), Pharmacoepidemiol drug saf, 33
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Preventable hand injuries: A national audit.
Journal article
Lane JCE. et al, (2023), Jpras open, 38, 305 - 312
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Statistics for the hand surgeon. Part 2: avoiding common pitfalls.
Journal article
Harvey MR. et al, (2023), J hand surg eur vol, 48, 1237 - 1243
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Statistics for the hand surgeon. Part 1: principles and application to hand surgery research.
Journal article
Harvey MR. et al, (2023), J hand surg eur vol, 48, 1096 - 1102