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Researchers at the Kennedy Institute, University of Oxford have found that a single administration of a molecule accelerated healing of multiple tissues when administered after or even before injury.

News Items (14)

A more tailored approach to treating psoriatic arthritis

8 January 2021

Dr Laura Coates has been awarded £1.8M from the National Institute for Health Research (NIHR) to explore the potential for precision medicine in the choice of biologics to reduce inflammation and pain in psoriatic arthritis.

New breakthrough in the treatment of rheumatoid arthritis

25 November 2020

People with Rheumatoid Arthritis (RA) could soon benefit from a new drug treatment that not only suppresses inflammation but also significantly reduces patient reported pain scores. Otilimab is a monoclonal antibody, biologic drug, which targets and suppresses the inflammatory cytokine GM-CSF.

Key discovery in Psoriatic Arthritis points way for developing targeted treatments

21 September 2020

A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the strongest evidence yet of a single cause for the disease.

Workload linked with an increased risk of knee osteoarthritis

9 September 2020

Men and women working in heavy manual occupations are twice as likely to suffer from knee osteoarthritis (OA), the most common joint disorder, compared to those in sedentary occupations according to a new study published in the prestigious journal Seminars in Arthritis and Rheumatism.

Numerous jobs linked to increased risk of knee osteoarthritis

23 July 2020

Stay-at-home parents, cleaners, and blue-collar workers found to be more likely to develop osteoarthritis

Joint cell discovery offers new hope for people with rheumatoid arthritis

29 June 2020

The key to swift treatments to cure the pain of rheumatoid arthritis has been found in the joints of people with the condition who are in long- term remission.

Researchers identify markers in joint fluid that could be the key to cartilage repair

9 March 2020

Molecular changes in the joint fluid during surgical joint distraction reveal markers that may drive cartilage repair in osteoarthritis.

New therapeutic target identified in spondyloarthritis

20 January 2020

A new study published in Nature Communications identifies a key driver of joint and intestinal inflammation that could lead to future treatment of the chronic inflammatory disease.

Key link discovered between tissue cell type and different forms of arthritis

29 May 2019

Pioneering research by scientists at the Universities of Oxford and Birmingham published today in Nature brings us a step closer to developing targeted therapies for inflammatory diseases.

Study reveals new drug target for rheumatoid arthritis

28 May 2019

New research at the Kennedy Institute reveals potential of a novel class of drugs for the treatment of rheumatoid arthritis.

UKRI Future Leaders Fellowship to Dr Fiona Watt

7 May 2019

Dr Fiona Watt has been awarded a prestigious UK Research and Innovation (UKRI) Future Leaders Fellowship to further her research for better treatments for people living with, or at risk of the commonest form of arthritis, osteoarthritis.

New approach could bring closer a cure for a painful form of arthritis

1 April 2019

Dr Liye Chen has been awarded a Versus Arthritis five-year career development fellowship to identify and validate new T cell therapeutic targets in ankylosing spondylitis (AS).

Showcasing a new approach to arthritis research

27 March 2019

A recent workshop at Pembroke College, Oxford, provided a showcase for research within the Arthritis Therapy Acceleration Programme (A-TAP) aimed at speeding up the delivery of new drugs for immune-mediated inflammatory disease (IMIDs).

New drug class could offer a targeted safer treatment alternative for patients with rheumatoid arthritis

15 February 2019

A new treatment targeting tenascin-C could reduce the progression and severity of rheumatoid arthritis (RA) at the very early stages of disease.

Meet the team

Jagdeep Nanchahal

Professor of Hand, Plastic and Reconstructive Surgery
Ana Isabel Espirito Santo

Postdoctoral Researcher
Fiona Powrie FRS

Professor of Musculoskeletal Sciences and Director of the Kennedy Institute
Sir Marc Feldmann FRS

Emeritus Professor

Read the paper

Fully reduced HMGB1 accelerates the regeneration of multiple tissues by transitioning stem cells to GAlert

Proc Natl Acad Sci U S A. 2018 Apr 19

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Patients and carers invited to join new group helping to shape research and treatment of bones, muscles and joints

5 March 2021

Oxford’s newest patient partner group, OPEN ARMS launches today to explore the causes, treatment and care for patients with musculoskeletal conditions. Its first three patient partners explain why they are involved and invite other members of the public to join the team.

NDORMS academics named NIHR Senior Investigators

5 March 2021

Congratulations to Professor Jonathan Rees who has been announced as a National Institute of Health Research (NIHR Senior Investigator).

New centre aims to help companies conduct more efficient trials

26 February 2021

A new clinical therapeutics centre has been set up by the University of Oxford to help life sciences companies identify interventions that have the greatest potential to deliver patient benefit, and so bring down the cost of early phase clinical trials.