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Researchers at NDORMS have found that many more patients could be given a partial knee replacement instead of a total knee replacement, resulting in improvements in their quality of life and lower costs for the healthcare system.

Medical examination of knee

Versus Arthritis invests in ‘team science’ to meet pressing challenges faced by people with arthritis

Researchers at the Botnar Institute have joined a new consortium that has been awarded £3m from the charity Versus Arthritis to bring world-leading experts from five UK universities together to accelerate clinical epidemiology research, which will help answer pressing questions from those living with arthritis.

NDORMS researchers awarded Associate Professor title

Ghada Alsaleh and Alex Clarke have been awarded the title of Associate Professor by the University of Oxford.

Professor Andrew Carr recognised in King’s Birthday Honours

Professor Andrew Carr was honoured in the 2025 King’s Birthday Honours List being awarded an MBE for services to Orthopaedic Research and Training.

NDORMS researchers search for the ‘achilles heel’ of chondrosarcoma

A new study to better understand the deadly bone cancer chondrosarcoma aims to reveal potential 'weak spots' of the disease with the ultimate goal of developing more effective treatments for patients.

Psoriatic arthritis: hit hard and early

Laura Coates presents the results from the 'SPEED' trial that found early use of biologic therapy or combination conventional DMARDs may be more effective than standard step-up care with methotrexate for psoriatic arthritis patients with poor prognostic factors.

New research identifies key driver of inflammation in spondyloarthritis

NDORMS researchers have identified a primary source of inflammatory IL-17 driving spondyloarthritis, paving the way for the development of targeted therapies to treat the condition.

David Keene appointed to Kadoorie Professorship of Trauma Rehabilitation

David Keene will lead advanced research and teaching in trauma rehabilitation at Oxford Trauma and Emergency Care within NDORMS.

New NDORMS study looking for a breakthrough in osteosarcoma

The Bone Cancer Research Trust and Sarcoma UK are joining forces to launch two groundbreaking research projects which could support the early diagnosis of primary bone cancer.

Professor Amar Rangan announced as new Fellow of the Academy of Medical Sciences

Professor of Orthopaedic Surgery Amar Rangan has been recognised as an exceptional health scientist in his election as a Fellow of the Academy of Medical Sciences.

Speedy diagnosis and treatment are key for wrist injury patients

A new study supports the strategy of using early MRI scans to significantly improve care and experiences for patients with wrist injuries.

NDORMS researchers deliver pioneering treatment for rare genetic condition

A team at NDORMS, University of Oxford has successfully administered a pioneering treatment to a patient with XIAP deficiency, a rare genetic disorder.

TCRs drive CARs

Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer treatments. This study, published in Cell, demonstrates that engineering T-cells to express both a Chimeric Antigen Receptor (CAR) and a T-cell Receptor (TCR) can improve their ability to distinguish between cancerous and healthy tissues—addressing a major challenge in current immunotherapy.

Multilingual animations launched

Common virus may improve skin cancer treatment outcomes, study finds

A new study led by the University of Oxford has revealed that a common and usually harmless virus may positively influence how skin cancer patients respond to current treatments.

CRUK funding for research into earlier detection of relapse in people with multiple myeloma

Dr Karthik Ramasamy and team will assess a new mass spectrometry-based monitoring technique for its ability to predict and identify early disease relapse.

New ultrasound drug delivery system found to be highly effective against bacterial biofilms

Researchers at the University of Oxford have developed a new drug delivery system using ultrasound-activated nanoparticles to break through and destroy bacterial biofilms. This offers a promising solution that could address the global crisis of chronic antibiotic-resistant infections affecting hundreds of millions of people worldwide.

New research highlights colorectal cancer trends and survival rates

A recent study published in the American Journal of Gastroenterology investigates the incidence and survival rates of colorectal cancer (CRC) in the UK. The research offers healthcare decision-makers crucial insights for planning, management and screening for colorectal cancer.

New CONSORT reporting guidelines published today in five medical journals

The CONSORT 2025 statement, an updated guideline for reporting randomised trials is being simultaneously published in The BMJ, JAMA, The Lancet, Nature Medicine, and PLOS Medicine.

NDORMS leads study on burosumab for adults with rare inherited disorder

NDORMS researchers have been awarded funding to explore the long-term effects of burosumab in adults with X-linked hypophosphataemia (XLH).

Blood cancer patients should continue treatment at time of COVID-19 vaccination, OCTRU study shows

Evidence shows for patients with a type of leukaemia, pausing BTKi therapy for COVID-19 vaccination does not improve antibody responses to the vaccine

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Cost-effectiveness of unicompartmental compared with total knee replacement: a population-based study using data from the National Joint Registry for England and Wales

BMJ Open, April 30

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