Contact information

Email	rafael.pinedo@ndorms.ox.ac.uk
Tel	+44 1865 223430

My connections

MRC Lifecourse Epidemiology Unit University of Southampton
Rare diseases RUDY Study

Arden Group | Epidemiology of Musculoskeletal Diseases Research Group
Judge Group | Health Service Delivery Research Group
Prieto-Alhambra Group | Musculoskeletal Pharmaco- and Device epidemiology Research Group
Big Health Data Research Research Group
Javaid Group | Rare Bone Diseases and Osteoporosis Epidemiology Research Group
UTMoSt Research Group

Rafael Pinedo Villanueva

BA, MSc, MSc, PhD

Senior Research Associate in Health Economics

I trained in Economics and Political Science at the University of Michigan (USA) and later received an MSc in Political Science (Public Policy) from Universidad Simon Bolivar (Venezuela). After several years of experience working in two United Nations agencies, lecturing in economics and conducting research in the health sector I moved into health economics. I completed an MSc in Health Economics at the University of York and subsequently received a PhD from the University of Southampton with a thesis exploring the cost-effectiveness of an outcome prediction tool for total hip replacements in the UK.

As a health economist based at NDORMS and affiliated to the Medical Research Council Lifecourse Epidemiology Unit in Southampton, my research focuses on the economics of musculoskeletal diseases and interventions.

I am mostly interested in using large routinely collected datasets to better understand the resources used and costs associated to the care of patients as they go through both primary and secondary care providers, and their outcomes after specific interventions.

One of my main areas of study has been the costs and outcomes after arthroplasties of the hip and knee using data from the Clinical Practice Research Datalink (CPRD), Hospital Episode Statistics (HES) and the national PROMs programme.

I am also particularly interested in the impact on health-related quality of life of patients with musculoskeletal diseases whether they have had surgical, non-surgical or no interventions at all.

I lead health economics work packages within locally and nationally-funded programmes on the prediction of outcomes after joint replacement, improved management of post-surgical chronic pain, economic evaluation of novel surgical procedures and care pathways, re-design of exercise rehabilitation programmes, and long-term assessment of interventions during pregnancy, amongst others.

My work is largely cross-disciplinary as it explores the potential value for money of interventions in osteoarthritis, rare diseases of the bone, sarcopenia, and other musculoskeletal diseases, which I conduct working closely with epidemiologists, rheumatologists, statisticians, GPs, surgeons, and patients themselves. The ultimate aim of this research is to improve patients' outcomes by informing public policy in healthcare.

Improving patient outcomes in fibrous dysplasia/McCune-Albright syndrome: an international multidisciplinary workshop to inform an international partnership.
Boyce AM. et al, (2017), Archives of osteoporosis, 12
A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies
Brindley DB. et al, (2017), Journal of Tissue Engineering
Lower limb arthroplasty: can we produce a tool to predict outcome and failure, and is it cost-effective? An epidemiological study
Arden N. et al, (2017), Programme Grants for Applied Research, 5, 1 - 246
Choosing Between Unicompartmental and Total Knee Replacement: What Can Economic Evaluations Tell Us? A Systematic Review
Burn E. et al, (2017), PharmacoEconomics - Open
Ten-year patient-reported outcomes following total and minimally invasive unicompartmental knee arthroplasty: a propensity score-matched cohort analysis.
Burn E. et al, (2016), Knee Surg Sports Traumatol Arthrosc
Health-related quality of life and a cost-utility simulation of adults in the UK with osteogenesis imperfecta, X-linked hypophosphatemia and fibrous dysplasia.
Forestier-Zhang L. et al, (2016), Orphanet J Rare Dis, 11
The RUDY study platform - a novel approach to patient driven research in rare musculoskeletal diseases.
Javaid MK. et al, (2016), Orphanet J Rare Dis, 11
THE COST EFFECTIVENESS OF EXERCISE-BASED CARDIAC REHABILITATION: A SYSTEMATIC REVIEW
Edwards K. et al, (2016), British Journal of Sports Medicine, 50, 1351.1 - 1351
World Hip Trauma Evaluation (WHiTE): framework for embedded comprehensive cohort studies.
Costa ML. et al, (2016), BMJ open, 6
WORSE OFF AFTER KNEE REPLACEMENTS: HOW LIKELY IS IT AND WHAT ROLE DOES THE PRE-OPERATIVE OXFORD KNEE SCORE PLAY? EVIDENCE FROM THE ENGLISH NHS
Pinedo-Villanueva R. et al, (2016), OSTEOARTHRITIS AND CARTILAGE, 24, S35 - S36
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2016): Poster Abstracts
(2016), Osteoporosis International, 27, 79 - 548
RHEUMATOID FACTOR TESTING IN SPANISH PRIMARY CARE COSTS (sic)1432 PER TRUE POSITIVE CASE OF RHEUMATOID ARTHRITIS; A STUDY USING ELECTRONIC DATA FROM THE INFORMATION SYSTEM FOR THE DEVELOPMENT OF RESEARCH IN PRIMARY CARE
Morsley K. et al, (2015), RHEUMATOLOGY, 54, 67 - 67
A reference case for economic evaluations in osteoarthritis: an expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).
Hiligsmann M. et al, (2014), Seminars in arthritis and rheumatism, 44, 271 - 282
Diagnostic Accuracy and Associated Costs of Rheumatoid Factor Testing in Primary Care: A Population-Based Cohort Study in Spain
Luqmani R. et al, (2014), ARTHRITIS & RHEUMATOLOGY, 66, S157 - S158
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2014): Satellite Symposium Abstracts
(2014), Osteoporosis International, 25, 441 - 445
PRIMARY CARE COSTS ATTRIBUTABLE TO OSTEOARTHRITIS BEFORE TOTAL HIP REPLACEMENT
Pinedo-Villanueva R. et al, (2014), OSTEOARTHRITIS AND CARTILAGE, 22, S210 - S211
OUTCOMES AFTER TOTAL HIP REPLACEMENT
Pinedo-Villanueva R. et al, (2014), OSTEOARTHRITIS AND CARTILAGE, 22, S214 - S214
COST-EFFECTIVENESS OF TOTAL HIP REPLACEMENTS: A COMPREHENSIVE MODEL
Pinedo-Villanueva R. et al, (2014), RHEUMATOLOGY, 53, 31 - 31
Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study.
Davies BM. et al, (2014), Journal of tissue engineering, 5
PRImary care Streptococcal Management (PRISM) study: in vitro study, diagnostic cohorts and a pragmatic adaptive randomised controlled trial with nested qualitative study and cost-effectiveness study.
Little P. et al, (2014), Health technology assessment (Winchester, England), 18, vii - 101
The implementation of novel collaborative structures for the identification and resolution of barriers to pluripotent stem cell translation.
Brindley DA. et al, (2013), Stem cells and development, 22 Suppl 1, 63 - 72
ESTIMATING THE ASSOCIATION BETWEEN THE OXFORD HIP SCORE (OHS) AND EQ-5D UTILITY VALUES USING DIRECT AND RESPONSE MAPING METHODS
Rivero-Arias O. et al, (2013), VALUE IN HEALTH, 16, A600 - A600
USE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS IN YEAR 1 FOLLOWING TOTAL KNEE ARTHROPLASTY AND IMPLANT SURVIVAL: A REGISTER-BASED COHORT STUDY
Prieto-Alhambra D. et al, (2013), OSTEOARTHRITIS AND CARTILAGE, 21, S154 - S154
Mapping the Oxford hip score onto the EQ-5D utility index.
Pinedo-Villanueva RA. et al, (2013), Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 22, 665 - 675
PR2 The Beauty of Mapping: Need the Mean Health-Related Quality of Life Score for a Group of Hip Patients and Don't Have EQ-5D? Just Use the Oxford Hip Score!
Pinedo Villanueva RA. et al, (2011), Value in Health, 14, A541 - A541
¿Cómo se ha medido la posición social en investigación en salud?: una revisión de la literatura internacional
Cabieses B. et al, (2011), Revista Panamericana de Salud Pública, 29, 457 - 468
PCV82 ECONOMIC EVALUATION OF THE USE OF PERFLUOROCARBON EMULSION (PFC) VS. PERIOPERATIVE BLOOD TRANSFUSION IN CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS AT THE MEXICAN INSTITUTE OF SOCIAL SECURITY
Contreras I. et al, (2010)
Cost-utility of unicompartmental compared to total knee replacements: an analysis based on matched routinely-collected data from the United Kingdom
Burn E. et al

Key Publications

Health-related quality of life and a cost-utility simulation of adults in the UK with osteogenesis imperfecta, X-linked hypophosphatemia and fibrous dysplasia.
Forestier-Zhang L. et al, (2016), Orphanet J Rare Dis, 11
A reference case for economic evaluations in osteoarthritis: an expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).
Hiligsmann M. et al, (2014), Seminars in arthritis and rheumatism, 44, 271 - 282
Mapping the Oxford hip score onto the EQ-5D utility index.
Pinedo-Villanueva RA. et al, (2013), Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 22, 665 - 675

Recent Publications

Improving patient outcomes in fibrous dysplasia/McCune-Albright syndrome: an international multidisciplinary workshop to inform an international partnership.
Boyce AM. et al, (2017), Archives of osteoporosis, 12
A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies
Brindley DB. et al, (2017), Journal of Tissue Engineering
Lower limb arthroplasty: can we produce a tool to predict outcome and failure, and is it cost-effective? An epidemiological study
Arden N. et al, (2017), Programme Grants for Applied Research, 5, 1 - 246
Choosing Between Unicompartmental and Total Knee Replacement: What Can Economic Evaluations Tell Us? A Systematic Review
Burn E. et al, (2017), PharmacoEconomics - Open
Ten-year patient-reported outcomes following total and minimally invasive unicompartmental knee arthroplasty: a propensity score-matched cohort analysis.
Burn E. et al, (2016), Knee Surg Sports Traumatol Arthrosc

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