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A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

Macrophage engulfing bacteria 3d illustration © Shutterstock
The new study shows the IL-10-PGE2 axis ensures macrophages are effective at killing potentially harmful bacteria

Health Economics & Outcomes Research

Our research aims to improve people's health and wellbeing by making the most efficient use of health and social care resources. To achieve this, we use real-world data and mathematical models to evaluate the costs and consequences of applying different interventions over a period of time, often the entire lifetime of patients.

EMCAT

Ecological Momentary Computerised Adaptive Testing

MEET FIONA

  • Fiona Powrie FRS
    Fiona Powrie FRS

    Professor of Musculoskeletal Sciences and Director of the Kennedy Institute

FUNDED BY

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 Fondation Louis-Jeantet

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Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2
Journal of Experimental Medicine

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