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The Centre for Statistics in Medicine (CSM) has been awarded £2.5m by Cancer Research UK to advance a programme of work for research on research, developing crucial methodology and key guidelines for excellent medical research.
Botnar researchers awarded Fellowships
Arthritis Awards Botnar CSM Hand Main
9 January 2023
Arani Vivekanantham has been awarded an NIHR Doctoral Fellowship and a Versus Arthritis Clinical Research Fellowship, and Rachel Kuo was awarded an NIHR Doctoral Research Fellowship.
Better diagnosis and treatment of autoimmune diseases moves a step closer
Arthritis Main
5 January 2023
A study published in Nature outlines a way to find the crucial peptides (protein fragments) that drive autoimmunity, as well as the immune cells that respond to them.
NDORMS and GRAPPA launch new resource to help people suffering from psoriatic arthritis
Arthritis Main
7 April 2022
NDORMS and GRAPPA (the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis) have launched Informatree, a new web resource to help people living with Psoriatic Arthritis.
New funding awarded to study persistent pain in inflammatory arthritis
Arthritis Funding Kennedy Main
7 March 2022
The £3.9M Wellcome Collaborative Award will be used to identify the drivers of pain in people living with rheumatoid arthritis.
New research reveals link between ankle pain and onset of knee osteoarthritis
Arthritis Knee Main
16 November 2021
A new study published in Osteoarthritis and Cartilage Open could help improve the lives of people at risk of developing knee osteoarthritis.
New therapeutic targets identified in the treatment of psoriatic arthritis
Arthritis Botnar Main
16 July 2021
Researchers identify two inflammatory-driving proteins, osteopontin and CCL2, highly expressed in psoriatic arthritis joints.
Researchers show the role of cilia in cartilage health
Arthritis Kennedy Main
15 July 2021
New research shows that disrupting primary cilia in juvenile, adolescent and early adulthood in cartilage stops it maturing correctly, making it more prone to thinning and the potential for osteoarthritis (OA) in later life.
New research could improve quality of life for Psoriatic Arthritis patients
Arthritis Botnar Coronavirus COVID-19 Funding Main
2 July 2021
Professors Laura Coates and Dani Prieto-Alhambra will take major roles in a new European Commission project to develop innovative personalised treatment options for people affected by psoriatic arthritis.
Study finds marked differences in the use of ankle replacements across six countries
Arthritis Botnar Main
18 June 2021
A new study published in Foot and Ankle International reviews the use of ankle replacements across 6 countries to predict why there is a variance in their use, and to determine how far current demands are being met.
Hope for rheumatoid arthritis patients who are non-responsive to anti-TNF
Arthritis Kennedy Main
11 March 2021
New research published in The Lancet shows that tocilizumab is a more effective treatment than rituximab for rheumatoid arthritis patients with a poor response to anti-tumour necrosis factor (TNF).
A new study maps the expression of innate immune receptors during the course of arthritis
Arthritis Kennedy Main
8 March 2021
The research, which was a collaboration with researchers from Oxford University and Queen Mary University of London and published in Journal of Autoimmunity, looked at changes in receptors known as toll-like receptors (TLRs) in arthritis at different stages of disease.
A more tailored approach to treating psoriatic arthritis
Arthritis Botnar Funding Main
8 January 2021
Dr Laura Coates has been awarded £1.8M from the National Institute for Health Research (NIHR) to explore the potential for precision medicine in the choice of biologics to reduce inflammation and pain in psoriatic arthritis.
New breakthrough in the treatment of rheumatoid arthritis
Arthritis Kennedy Main
25 November 2020
People with Rheumatoid Arthritis (RA) could soon benefit from a new drug treatment that not only suppresses inflammation but also significantly reduces patient reported pain scores. Otilimab is a monoclonal antibody, biologic drug, which targets and suppresses the inflammatory cytokine GM-CSF.
Key discovery in Psoriatic Arthritis points way for developing targeted treatments
Arthritis Main
21 September 2020
A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the strongest evidence yet of a single cause for the disease.
Workload linked with an increased risk of knee osteoarthritis
Arthritis Main
9 September 2020
Men and women working in heavy manual occupations are twice as likely to suffer from knee osteoarthritis (OA), the most common joint disorder, compared to those in sedentary occupations according to a new study published in the prestigious journal Seminars in Arthritis and Rheumatism.
Numerous jobs linked to increased risk of knee osteoarthritis
Arthritis Main
23 July 2020
Stay-at-home parents, cleaners, and blue-collar workers found to be more likely to develop osteoarthritis
Joint cell discovery offers new hope for people with rheumatoid arthritis
Arthritis Kennedy Main
29 June 2020
The key to swift treatments to cure the pain of rheumatoid arthritis has been found in the joints of people with the condition who are in long- term remission.
Researchers identify markers in joint fluid that could be the key to cartilage repair
Arthritis Kennedy Knee Main
9 March 2020
Molecular changes in the joint fluid during surgical joint distraction reveal markers that may drive cartilage repair in osteoarthritis.
New therapeutic target identified in spondyloarthritis
Arthritis Kennedy Main
20 January 2020
A new study published in Nature Communications identifies a key driver of joint and intestinal inflammation that could lead to future treatment of the chronic inflammatory disease.
Key link discovered between tissue cell type and different forms of arthritis
Arthritis Kennedy Main Publication Translational medicine
29 May 2019
Pioneering research by scientists at the Universities of Oxford and Birmingham published today in Nature brings us a step closer to developing targeted therapies for inflammatory diseases.
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NHS baby check may miss dislocated hips in new-born babies
25 April 2024
A new study has identified that NHS infant checks can miss serious hip abnormalities in new-born babies. Left undetected, these can require complex surgery, and lead to early arthritis. In the UK around 500 infants undergo surgery for dislocated hips which could have been avoidable.