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Secondary school students attending the UNIQ Summer school visited NDORMS for a morning of talks, workshops and practicals.
NDORMS researchers awarded for Dupuytren research
Awards Hand Kennedy Main
8 April 2021
Three NDORMS researchers have received awards from the International Dupuytren Society, a patient organisation that brings together Dupuytren Disease patient societies from across the world.
Hope for rheumatoid arthritis patients who are non-responsive to anti-TNF
Arthritis Kennedy Main
11 March 2021
New research published in The Lancet shows that tocilizumab is a more effective treatment than rituximab for rheumatoid arthritis patients with a poor response to anti-tumour necrosis factor (TNF).
A new study maps the expression of innate immune receptors during the course of arthritis
Arthritis Kennedy Main
8 March 2021
The research, which was a collaboration with researchers from Oxford University and Queen Mary University of London and published in Journal of Autoimmunity, looked at changes in receptors known as toll-like receptors (TLRs) in arthritis at different stages of disease.
Vascular loss shown to be the primary hallmark of aging
Kennedy Main Tissue remodelling and regeneration
4 February 2021
New Research from the Kusumbe group at the Kennedy Institute of Rheumatology identifies vascular attrition, marked by pericyte to fibroblast differentiation, as a primary hallmark of aging and highlights organ-specific vascular changes with age.
Immunology preprint reviews launched in Nature Reviews Immunology
Kennedy Main Research
15 January 2021
The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.
Drug may boost vaccine responses in older adults
Kennedy Main
18 December 2020
A preliminary study shows that a drug which helps immune cells self-clean may improve vaccine protection in older adults
Living reviews launched by Oxford and Cardiff in the wake of COVID-19 research
Kennedy Main Research
18 December 2020
In a combined effort to help COVID-19 researchers the University of Oxford and Cardiff University have launched a series of “living reviews” in Oxford University Press’s new open access journal “Oxford Open Immunology”.
Oxford University awarded £2.4 million to fund DPhil research in inflammation, immunology and musculoskeletal disease
Awards Inflammation biology Kennedy Main
18 December 2020
Oxford University has today been awarded a £2.4 million grant, as part of the Kennedy Trust MB PhD scheme, to fund undergraduate medical students to undertake DPhil research in the areas of inflammation, immunology and musculoskeletal disease.
3D imaging reveals the role of blood vessels in hormone production
Kennedy Main Research
11 December 2020
New research from the Kusumbe Group at the Kennedy Institute has shown a direct correlation between age-related decline in capillary and artery numbers and hormone production in the endocrine system.
£3M invested to drive forward early translation through five new Oxford-Bristol Myers Squibb Fellowships
Awards Kennedy Main
10 December 2020
Five new Oxford-Bristol Myers Squibb Fellowships representing an investment of £3M have been announced. The fellowships (formerly Oxford-Celgene) will support postdoctoral researchers and clinicians across five departments within the Medical Sciences Division and the Mathematical, Physical and Life Sciences Division, providing an opportunity for them to gain exposure to the field of commercial drug discovery and development.
New breakthrough in the treatment of rheumatoid arthritis
Arthritis Kennedy Main
25 November 2020
People with Rheumatoid Arthritis (RA) could soon benefit from a new drug treatment that not only suppresses inflammation but also significantly reduces patient reported pain scores. Otilimab is a monoclonal antibody, biologic drug, which targets and suppresses the inflammatory cytokine GM-CSF.
Professor Katja Simon awarded Wellcome Trust Investigator Award
Funding Kennedy Main
13 November 2020
Professor Simon has been successful in her Wellcome Trust Investigator Award entitled: “Proteostasis and Autophagy in Immune Senescence.”
European Centre of Excellence at NDORMS
Awards Kennedy
3 November 2020
NDORMS has been designated a EULAR Centre of Excellence 2020-2025, in recognition of our continued high-quality research publications in rheumatology.
An unexpected repair function for neutrophils
Kennedy Main
30 October 2020
In a collaboration with scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), Kennedy researchers have contributed to the discovery that neutrophils have many more functions in the body than previously thought. This finding suggests that neutrophil tissue-specific plasticity could be exploited in designing new treatments for neutrophil driven diseases, including cancer.
Understanding the physics of the immune response necessitates new technology
Kennedy Main
23 October 2020
Professor Marco Fritzsche has joined the Kennedy Institute as the Principal Investigator of the Biophysical Immunology Laboratory (BPI), as part of a joint appointment with the Rosalind Franklin Institute. His lab is leading the development of a lattice light sheet microscope that will significantly advance the study of live cells.
CD2 corolla calls T cells to arms
Kennedy Main
20 October 2020
A team from the University of Oxford has visualised how key cells of the immune system lock onto cancerous or infected cells to destroy them. The work was led by the Mike Dustin’s group at the Kennedy Institute of Rheumatology and experts in colorectal and ovarian cancers from across Oxford and computational biologists at the University of Birmingham.
Likely culprits causing blood vessel lesions in vasculitis identified
Kennedy Main
19 October 2020
NDORMS researchers identify a subset of immune cells that could be a new therapeutic target to treat inflamed blood vessels in Giant Cell Arteritis (GCA) and other forms of inflammatory vascular disease.
Research review reveals potential to improve colon cancer treatments
Kennedy Main
2 October 2020
Researchers at the Kennedy Institute review the growing body of literature on the role of the microbiome in colorectal cancer
IL-22 pathway linked to poor prognosis in colon cancer
Kennedy Main Oncology
18 August 2020
Research shows how IL-22 interacts with KRAS mutant tumours to promote excessive growth in colorectal cancer
Marie Curie Fellowship awarded to Mariana Borsa
Kennedy Main
10 July 2020
Congratulations to Mariana Borsa for being awarded the Marie Skłodowska-Curie Actions – Individual Fellowship