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Secondary school students attending the UNIQ Summer school visited NDORMS for a morning of talks, workshops and practicals.
First of its kind study for children with arthritis reveals possible new disease targets
4 July 2025
Researchers have been able to see what happens in the inflamed joints of children with arthritis, giving insight into why treatments affect children differently.
New insights into chronic inflammation in rheumatoid arthritis
30 June 2025
Kennedy researchers have uncovered new clues about how immune memory exacerbates inflammation in rheumatoid arthritis, which could lead to better ways to control the disease.
Dr Chrissy Bolton wins Best Abstract Award at EULAR 2025 Congress
25 June 2025
Kennedy DPhil student Chrissy Bolton has been awarded Best Abstract in Basic and Translational Science at the European Alliance of Associations for Rheumatology 2025 (EULAR) conference.
Designing better bispecific T-cell engagers for cancer immunotherapy
19 June 2025
Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs) - a class of cancer immunotherapy drugs. The findings may help unlock the full potential of TcEs and revolutionise cancer treatment for patients.
NDORMS researchers awarded Associate Professor title
16 June 2025
Ghada Alsaleh and Alex Clarke have been awarded the title of Associate Professor by the University of Oxford.
NDORMS researchers deliver pioneering treatment for rare genetic condition
15 May 2025
A team at NDORMS, University of Oxford has successfully administered a pioneering treatment to a patient with XIAP deficiency, a rare genetic disorder.
TCRs drive CARs
1 May 2025
Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer treatments. This study, published in Cell, demonstrates that engineering T-cells to express both a Chimeric Antigen Receptor (CAR) and a T-cell Receptor (TCR) can improve their ability to distinguish between cancerous and healthy tissues—addressing a major challenge in current immunotherapy.
Common virus may improve skin cancer treatment outcomes, study finds
25 April 2025
A new study led by the University of Oxford has revealed that a common and usually harmless virus may positively influence how skin cancer patients respond to current treatments.
New research uncovers pathways to prevent premature cell death
28 March 2025
New research from the Kennedy Institute has revealed how two important proteins, TBK1 and IKKe, play a crucial role in preventing premature cell death, which can lead to serious inflammation in the body. The findings are particularly relevant for people with a mutation in the TBK1 gene who often develop multiorgan inflammation caused by excessive cell death even in the absence of any infection.
Decoding the interplay between genes and mechanics in tissues at single-cell resolution
17 March 2025
Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene expression and mechanical forces within cells and tissues, uncovering insights into how the interplay between transcriptional and mechanical signals guides processes such as cell fate decisions or the formation of spatially distinct tissue compartments.
Pancreatic cancer immune map provides clues for precision treatment targeting
7 February 2025
Study shows why there are differences in prognosis between different pancreatic tumours and identifies potential avenues for improved treatment approaches.
An interview with Audrey Gerard
21 January 2025
Audrey Gerard, an Associate Professor of Immune Cell Dynamics and Principal Investigator at the Kennedy Institute of Rheumatology, is working to understand how the immune response interacts with and shapes tumours.
Professor Michael Dustin named AAI Distinguished Fellow
20 January 2025
The American Association of Immunologists (AAI) has recognised the outstanding work of the Kennedy Institute’s Professor of Molecular Immunology Michael Dustin by naming him a Distinguished Fellow of AAI.
How an 'optional' amino acid is required for an optimal immune response
3 January 2025
A new study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.
Paul Kubes joins the Kennedy Institute as the Newton-Abraham Visiting Professor
9 December 2024
Paul joined the Kennedy Institute in September 2024 as part of the Newton-Abraham Visiting Professorship, a prestigious award given by the University of Oxford to the most distinguished scholars in the biological, chemical or medical sciences.
Dr Kate Coldwell awarded Daphne Jackson Fellowship to study links between liver disease and gut bacteria
17 September 2024
Dr Kate Coldwell has joined the Oxford Centre for Microbiome Studies at the Kennedy Institute to study the links between liver disease and gut bacteria, having been awarded the Daphne Jackson Fellowship, co-funded by the Kennedy Trust for Rheumatology Research (KTRR) and the Medical Research Council.
Kennedy scientists honoured with Royal Society Medal
16 September 2024
Professor Sir Ravinder Maini and Professor Sir Marc Feldmann have jointly received The Royal Society’s Royal Medal (Applied) for inventing anti-TNF therapy to treat rheumatoid arthritis (RA), bringing it from bench to bedside in one of the biggest success stories of modern medicine.
CRUK funding will help develop new targets for ovarian cancer
21 August 2024
Irina Udalova has received funding from Cancer Research UK (CRUK) to study the diverse role of neutrophils in ovarian cancer.
The Kennedy Institute welcomes Distinguished Investigator Dr Alan Sher
4 June 2024
Alan has spent two months at the Kennedy Institute as a guest of Professor Dame Fiona Powrie. During his visit he has spent his time collaborating with researchers at the Kennedy and other departments in the University, and mentoring young investigators on their career development.
Oxford researchers contribute to report on the future of healthcare
23 May 2024
Prof. Michael Dustin was one of 17 researchers from across Oxford's Medical Sciences and Maths, Physics and Life Sciences Divisions that have contributed to a new report on the future of healthcare, compiled by Citi Global Perspectives & Solutions (Citi GPS).