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Search results

Found 31106 matches for

UKUFF

The UKUFF Trial (funded by the Department of Health’s NIHR Health Technology Assessment programme) is a multi-centre randomised controlled trial to measure the clinical and cost effectiveness of different types of surgery for rotator cuff repairs. The study started in 2008 and was completed in 2014.

TOPKAT

The TOPKAT clinical trial, is a multi-centre randomised trial to measure the clinical and cost effectiveness of total and partial knee replacements for medial compartmental osteoarthritis.

BOOST

DCVAS

DCVAS is a multinational, observational study designed to develop and validate diagnostic criteria and to improve and validate classification criteria in vasculitis, a group of diseases where inflammation of blood vessels is the common feature.

BisCK

Patients with chronic kidney impairment suffer from bone fragility. Yet, most fracture protective therapies are contraindicated for them due to uncertainty on specific safety issues. We will use anonymised electronic medical records data from patients who have used first line anti-osteoporosis treatments (i.e. The so called bisphosphonates) to explore their potential benefits (fracture risk reduction) and risks.

BOOST

PATH-2

A pragmatic multi-centre, blinded, randomised placebo-controlled trial comparing Platelet Rich Plasma injection (PRP) to placebo (imitation) injection in adults with Achilles tendon rupture. Two sub-studies are embedded within the main study to contribute to the understanding of the PRP mechanism in tendon healing.

UK STAR

UK Study of Tendo Achilles Rehabilitation

WHITE-4

World Hip Trauma Evaluation Four

NINJA

NINJA-P

The NINJA study is a pilot study which will assess whether a study that looks at whether nail plates should be discarded or replaced after nail bed injury in children is feasible in the NHS.

Synthesising a clinical Prognostic Rule for Ankle INjuries in the Emergency Department (SPRAINED)

PROVE

The Physiotherapy Rehabilitation for Osteoporotic Vertebral Fracture (PROVE) study is a clinical trial planning to compare usual care versus an exercise based intervention versus a manual therapy based intervention. It aims to recruit 600 patients from centres across the UK.

RIDD

The RIDD trial aims to test whether the progression of Dupuytren’s disease can be halted or slowed by treatment with anti-TNF injection. Currently, Dupuytren’s disease is left to progress until the finger deformity is severe enough to warrant a surgical procedure in hospital. If successful, anti-TNF treatment would prevent loss of hand function and the need for surgery, and would allow patients to be treated conveniently and quickly.

OVIVA

To determine whether oral antibiotics are non-inferior to intravenous antibiotics for serious bone and joint infection judged by the percentage of patients experiencing definitive treatment failure during 1 year of follow up.

CSAW

NDORMS coordinated this multicentre randomised controlled trial (RCT) at 32 hospitals in the UK with 51 surgeons via the Surgical Intervention Trials Unit (SITU) and in collaboration with co-chief investigators Professors David Beard and Andrew Carr. The trial was funded by Arthritis Research UK (Ref.19707)

CORKA

The CORKA study was developed in response to a commissioned call by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme for research into a functional home based rehabilitation programme for patients who may be at risk of poor outcome after knee arthroplasty.

Powrie Group | Mucosal Immunology

The Powrie lab employs basic and translational science to study host-microbe crosstalk in health and disease, focussing on inflammatory bowel disease (IBD), colorectal cancer (CRC) and inflammatory arthritis. Research spans observational and functional analysis of a broad range of cell types including bacteria, fibroblasts, T cells and neutrophils.

Nanchahal Group | Treating Fibrosis and Improving Tissue Regeneration

Sansom Group | Computational and Single Cell Genomics Group

Work in the Sansom lab focuses on identifying the cellular and molecular causes of immune mediated inflammatory disease (IMID) using systems-level approaches.

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